表面增强拉曼技术在中药污染物检测中的应用与展望

Recent advances in surface-enhanced Raman scattering technique for pollutant detection in Chinese medicinal material

中药材是中医药行业的基础,中药材质量问题关乎居民健康生活和国家中医药行业的发展。农药残留、重金属、真菌毒素等是影响中药材质量的主要因素。目前,应用于污染物快速检测的方法层出不穷,表面增强拉曼光谱技术因其快速、无损的优点已在食品化学、环境分析等领域广泛应用,在中药污染物检测领域同样表现出巨大潜力。该文将回顾表面增强拉曼光谱技术在中药常见污染物的检测应用,重点讨论其用于农药残留检测的特点和优势,包括检测原理、基底设计、农药特异性识别等方面,为中药中多农药残留快速检测提供思路。

Chinese medicinal material is the foundation of traditional Chinese medicine(TCM)industry.Its quality is not only closely related to the health of residents but also the key to the development of the TCM industry.Pesticide residues,heavy metals and mycotoxins are the major pollutants of Chinese medicinal materials.In recent years,quite a number of rapid detection methods for pollutants have been constructed.Among them,surface-enhanced Raman scattering(SERS),which has been widely used in food chemistry,environmental analysis,and other fields because of its speediness and non-destructiveness,shows its great potential in the pollutant detection in Chinese medicinal material.This paper firstly reviews the application of SERS for the detection of common pollutants in Chinese medicinal material.We then discussed the characteristics and advantages of SERS technique for pesticide detection,including the principle,SERS substrate design,specific recognition,etc.Finally,simultaneous detection of multiple pesticide residues in Chinese medicinal material was explored.