摘要
四君子汤是临床常用的补益剂,现代研究发现四君子汤可从调节免疫、保护肠黏膜屏障、抗氧化应激、降低γ-氨基丁酸(GABA)水平、增加端粒活性、调节肠道菌群等方面对溃疡性结肠炎(UC)起到治疗作用。
Sijunzi Decoction is a commonly used supplement in clinical practice.Modern research has found that Sijunzi Decoction can play a therapeutic role in ulcerative colitis from the aspects of regulating immunity,protecting intestinal mucosal barrier,antioxidant stimulation,reducing GABA level,increasing telomere activity and regulating intestinal flora.
作者
杨维肖
李毅
李荣荣
白先
YANG Wei-xiao;LI Yi;LI Rong-rong;BAI Xian(The First Clinical Medical College of Shaanxi University of Traditional Chinese Medicine,Xianyang Shaanxi 712000,China;Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang Shaanxi 712000,China)
出处
《中医药导报》
2021年第2期92-96,100,共6页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(81803951)
陕西省重点研发项目(S2018-YF-YBSF-0407)
陕西省中医药管理局项目(2019-ZZ-LC001)。
关键词
四君子汤
溃疡性结肠炎
治疗机制
研究进展
Sijunzi decoction
ulcerative colitis
therapeutic mechanism
research progress
