摘要
猪带绦虫是重要的人体寄生虫之一,其幼虫和成虫均可致病,其中以幼虫——囊尾蚴引起的脑囊虫病造成的危害最为严重。囊尾蚴感染引起宿主的免疫反应及其调控机制一直是该病防治研究的重难点问题。作者就T淋巴细胞参与囊虫病的免疫应答及其免疫调控作用的研究进展做一综述,旨在为囊虫病的免疫发病机制及其防治研究提供相应的理论基础。
Taenia solium is one of the main human parasites.Both larvae and adults can cause diseases,among which neurocysticercosis caused by Cysticercus is the most serious disease.The immune response induced by Cysticercus infection and its regulatory mechanism have been the key problems in the prevention and treatment of Cysticercus infection.This review reports the progress of T lymphocytes-mediated immune responses and immunoregulation in cysticercosis,which is expected to provide a theoretical basis for the immunopathogenesis and prevention and treatment of cysticercosis.
作者
范贤敏
周必英
Fan Xianmin;Zhou Biying(Department of Parasitology,Zunyi Medical University,Zunyi 563000,China)
出处
《中华地方病学杂志》
CAS
北大核心
2021年第2期164-168,共5页
Chinese Journal of Endemiology
基金
国家自然科学基金(81960378)
贵州省优秀青年科技人才基金(黔科合平台人才[2017]5629)
贵州省教育厅青年科技人才成长项目(黔教合KY字[2018]225)
贵州省卫健委科研项目(gzwjkj2019-1-224)。
关键词
T淋巴细胞
囊虫病
免疫调控
T lymphocytes
Cysticercosis
Immunoregulation
