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普罗布考联合阿托伐他汀治疗脑梗死患者临床疗效研究

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摘要 目的:研究普罗布考联合阿托伐他汀治疗脑梗死患者临床疗效。方法:116例脑梗死患者作为本次研究对象,将其随机等分为对照组和观察组,对照组采用阿托伐他汀治疗,观察组在对照组基础上加用普罗布考治疗。结果:治疗后患者的全血高切黏度、全血低切黏度和血浆黏度均明显降低,且观察组降低程度明显高于对照组(P<0.05)。治疗后两组NIHSS评分均降低,且观察组降低程度明显高于对照组(P<0.05)。结论:普罗布考联合阿托伐他汀治疗脑梗死可降低患者血液黏稠度,促进神经损伤恢复,有效提升治疗效果,具有推广应用价值。
作者 罗剑木
出处 《中国农村卫生》 2021年第3期94-95,共2页
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  • 1汪洋.血塞通与弥可保联用治疗糖尿病周围神经病变疗效观察[J].西北药学杂志,2005,20(5):229-229. 被引量:3
  • 2Zhang Y, Huang S, Wang B, et al. Atorvastatin and whisker sIimulation synergistically enhance angiogenesis in the barrel cortex of rats following focal ischemia. Neurosci l.ett, 2012, 525,135- 139.
  • 3Lampl Y, Lorberboym M, C-ilad R, et al. Early outcome of acute ischemic stroke in hyperlipidemic patients under atorv astatin versus simvastatin. Clin Neuropharmacol, 2010, 33: 129 -134.
  • 4Massaro M, Zampolli A, Scoditti E, et al. Statin inhibit cy clooxygenase 2 and matrix melalloproteinase 9 in human en dothelial cell: anti angiogenic actions possibly contributing to plaque stability. Cardiovasc Res,2010,86:311- 320.
  • 5Nichrcinin D,Asplund K, Asberg S,et al. Statin therapy and outcome after ischemic stroke: systematic review and meta analysis of observational studies and randomized trials. Stroke,2013,44:448 -456.
  • 6他汀类药物防治缺札性卒中/短暂性腑i缺i缸发作专家组.他汀类药物防治缺血性卒中/短暂性脑缺血发作专家共识.中国卒中杂志,2013,8:565-575.
  • 7Amarenco P, Bogousslavsky J, Callahan A, et al. High dose atorvastation after stroke or transient isehemic attack. N Engl J Med,2006,355:549- 559.
  • 8Niimi M,Keyamura Y,Nozako M,et al. Prohucol inhibits the initiation of atherosclerosis in cholesterol fed rabbits. I.ipids Health Dis,2013,12:166 -173.
  • 9l.i S, Liang J, Niimi M, et al. Probucol suppresses macrophage infiltrotion and MMP expression in atherosclerotic plaques of WHHL rabbits. J Atheroscler Thromb,2014,21:648- 658.
  • 10Yamashita S, Matsuzawa Y. Where are we with probucol: a new life for an old drug? Atherosclerosis, 2009,207 : 16 -23.

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