基于“治未病”思想的各证型后循环TIA危险因素分析

The Analysis of Risk Factors of Posterior Circulation TIA of Different Patterns Based on the Thinking of“Preventive Treatment”

目的:探讨后循环短暂性脑缺血发作(transient ischemic attack,TIA)患者危险因素分布情况,分析后循环TIA各证型与相关危险因素之间的相关性。方法:参照2006年发布的《中国后循环缺血的专家共识》和《短暂性脑缺血发作的中国专家共识》,选择200例后循环TIA患者,根据《中医内科学》进行中医辨证分型,分析患者的一般资料(包括性别、年龄、吸烟、饮酒史等)、相关疾病史(包括高血压病、糖尿病、冠心病、既往卒中史、高脂血症等)。结果:所纳入的200例后循环TIA患者中,痰湿中阻组和瘀血阻窍组在性别分布方面差异有统计学意义(P<0.05),各证型组在年龄、烟酒分布方面差异无统计学意义(P>0.05)。后循环TIA患者中,合并高血压142例,其次为高脂血症87例,高同型半胱氨酸症59例;既往卒中史45例,冠心病45例,糖尿病42例,各证型组在疾病史分布方面差异无统计学意义(P>0.05)。结论:高血压是后循环TIA最重要的危险因素,痰湿中阻证和瘀血阻窍证是值得关注的证型,积极改善后循环TIA危险因素对缺血性脑卒中的防治具有重要意义。

Objective:To explore the distribution of risk factors for the patients with posterior circulation TIA,and analyze the connections between different patterns and the related risk factors.Methods:According to expert consensus on posterior circulation ischemia in China and Chinese expert consensus on transient ischemic attack published in 2006,200 TIA patients were selected and classified into different patterns in light of textbook of internal medicine of TCM,general information(including gender,age,smoking,drinking history and others)and related disease history(containing hypertension,diabetes mellitus,coronary heart disease,past stroke history,hyperlipidemia and others)of the subjects were analyzed.Results:Among all the included patients,the difference showed statistical meaning in the gender distribution between the groups of phlegm dampness obstructon and blood stasis obstructing the orifices(P<0.05),the difference had no statistical meaning in age,the distribution of smoking and alcohol among different groups of patterns(P>0.05).Among TIA patients,there were 142 patients complicated with hypertension,next 87 patients with hyperlipidemia,59 ones with hyperhomocysteinemia;45 patients had past stroke history,45 patients with CHD and 42 with DM,the difference showed no statistical meaning in disease history among different patterns groups(P>0.05).Conclusion:Hypertension is the most important risk factor for postcirculation TIA,phlegm dampness obstructon and blood stasis obstructing the orifices are the two patterns that deserve your attention,positively improving risk factors are significant for the prevention and treatment of TIA.