心脏磁共振细胞外容积在高血压性心脏病中的应用

Application of cardiac magnetic resonance extracellular volume in hypertensive heart disease

血压长期增高会引起心脏后负荷增加,导致高血压性心脏病。高血压性心脏病的主要改变是左心室肥厚及弥漫性心肌纤维化。通过心脏磁共振T1 mapping测量的细胞外容积作为无创性评估心肌纤维化的手段,在高血压性心脏病的诊断中发挥了重要的作用。作者就高血压性心脏病心肌纤维化的病理生理、高血压性心脏病细胞外容积的特点,治疗后细胞外容积的变化及细胞外容积与心脏磁共振其他技术的在高血压性心脏病中的联合应用进行综述。

Long-term increase in blood pressure can cause increased cardiac afterload,leading to hypertensive heart disease(HHD).The main changes of hypertensive heart disease are left ventricular hypertrophy and diffuse myocardial fibrosis.The extracellular volume(ECV)measured by cardiac magnetic resonance(CMR)T1 mapping is used as a non-invasive means to assess myocardial fibrosis and plays an important role in the diagnosis of hypertensive heart disease.The author discusses the pathophysiology of myocardial fibrosis in hypertensive heart disease,the characteristics of the extracellular volume of hypertensive heart disease,the change of extracellular volume after treatment,the extracellular volume and other techniques of cardiac magnetic resonance in hypertensive heart disease.The joint application of the company is reviewed.