膀胱过度活动症治疗药物临床研究进展

Clinical research progress on therapeutic drugs for overactive bladder

膀胱过度活动症是一种临床常见病,对患者生活质量造成显著影响,药物治疗是重要手段之一。本文对近年来膀胱过度活动症治疗药物临床研究的进展进行了综述,分析了上市以及临床研发阶段抗胆碱药物、β3-受体激动剂的临床特点及应用趋势,包括A型肉毒毒素的临床研究情况,并对该类疾病治疗药物临床试验设计的关键要素进行总结分析,以期为临床研发提供参考。

Overactive bladder is a common disease, which has a significant impact on the quality of life.We reviewed the progress of clinical research on therapeutic drugs for overactive bladder in recent years, while analyzed the clinical characteristics and application trend of anticholinergic drugs and β 3-receptor agonists, including the clinical research of botulinum toxin A, and summarized the key elements of clinical trial design.We hope to provide some help for clinical research and development.