高龄产妇产褥期感染的病原菌分布及耐药特征分析

Distribution and drug resistance characteristics of pathogenic bacteria in elderly women with puerperal infection

目的探究高龄产妇产褥期感染的病原菌分布及耐药特征分析。方法选取2017年1月至2019年10月在武汉儿童医院分娩的523例高龄产妇作为研究对象,其中50例发生产褥期感染。采集感染产妇标本,进行病原菌鉴定及药敏试验。分析产褥期感染患者的病原菌及病原菌的耐药率。结果产褥期感染产妇50例,感染率9.56%,会阴切口感染发生率最高为44.00%。共分离病原菌28株,其中以革兰阴性菌为主,大肠埃希菌、铜绿假单胞菌占多数,革兰阳性菌以溶血性链球菌为主。三种主要病原菌对亚胺培南均敏感。大肠埃希菌对头孢他啶较为耐药,铜绿假单胞菌对左氧氟沙星较为耐药,两者对庆大霉素较强耐药。溶血性链球菌对头孢吡肟较为耐药,对替考拉宁未出现耐药。结论高龄产妇产褥期感染的病原菌对多数抗菌药物耐药。

Objective To investigate the distribution and drug resistance characteristics of pathogenic bacteria in elderly women with puerperal infection.Methods A total of 523 elderly women who were delivered in our hospital from January 2017 to October 2019 were enrolled in the study.Among them,50 cases were infected with pneumonia.Infected maternal specimens were collected for pathogen identification and drug susceptibility testing.The resistance rate of pathogens and pathogens in patients with puerperal infection were analyzed.Results There were 50 cases of puerperal infections,the infection rate was 9.56%,and the highest incidence of perineal incision infection was 44.00%.A total of 50 pathogens were isolated,of which Gram-negative bacteria were dominant,Escherichia coli and Pseudomonas aeruginosa were the majority,and Gram-positive bacteria were mainly hemolytic streptococcus.The three major pathogens were sensitive to Imipenem.Escherichia coli was more resistant to Ceftazidime,and Pseudomonas aeruginosa was more resistant to levofloxacin,both of which were more resistant to gentamicin.Hemolytic streptococcus was more resistant to cefepime and no resistance to teicoplanin.Conclusion The pathogens of maternal puerperal infection are resistant to most antibiotics.