两种不同肺叶切除术治疗非小细胞肺癌的疗效观察

Efficacy of two different lobectomies in the treatment of non-small cell lung cancer

目的探讨两种不同肺叶切除术对非小细胞肺癌患者的治疗效果。方法选取2017年6月至2019年6月间咸阳市第一人民医院收治的104例早期非小细胞肺癌患者,根据采用的手术方法不同进行分组。采用全胸腔镜肺叶切除手术治疗的52例患者纳入试验组,采用传统开胸手术治疗的52例患者纳入对照组。比较两组患者的术后疼痛评分、并发症发生率、免疫功能和炎症因子水平。结果术后,试验组患者的疼痛评分和并发症发生率均低于对照组患者,差异均有统计学意义(均P<0.05);两组患者免疫因子较术前均降低,且试验组降低程度优于对照组,差异均有统计学意义(均P<0.05);两组患者炎症因子水平较术前均升高,且试验组升高程度低于对照组,差异均有统计学意义(均P<0.05)。结论肺癌患者采用电视胸腔镜手术可有效减少患者并发症,降低疼痛,有效抑制炎症因子表达,达到良好的治疗效果。

Objective To compare the therapeutic efficacy of two kinds of lobectomies in the treatment of non-small cell lung cancer.Methods One hundred and four patients with early stage non-small cell lung cancer who were diagnosed and treated at Xianyang First People’s hospital from June 2017 to June2019 were selected.Fifty-two patients undergoing total thoracoscopic lobectomy were included in an experimental group and 52 patients undergoing thoracotomy were included in a control group.Postoperative pain scores,the incidence of complications,immune function and levels of inflammatory factors were compared between the two groups.Results After the operation,the pain score and the incidence of complications rate were significantly lower in the experimental group than in the control group(all P<0.05).Three days after the operation,the immune factors were reduced in the two groups compared with those before the operation,and the reduction degree was significantly better in the experimental group than in the control group(all P<0.05).After the operation,the levels of inflammatory factors in both groups were significantly increased,and the degree of increase was significantly lower in the experimental group than in the control group(all P<0.05).Conclusion video-assisted thoracoscopic surgery can effectively reduce complications,reduce pain and inhibit the expression of inflammatory factors in lung cancer patients.