中医防治卵巢过度刺激综合征研究进展

Research Progress of Chinese Medicine Prevention and Treatment for Ovarian Hyper-stimulation Syndrome

卵巢过度刺激综合征(OHSS)作为辅助生殖技术最严重、最常见的并发症之一,其发病率逐年上升。目前临床仍缺乏有效的预防及治疗手段,而中医药在防治OHSS方面有着独特的优势。OHSS的病因病机主要为脾肾两虚,水湿内停;阴虚阳亢,气血瘀阻;血分失和,水饮停聚三个方面。中医对OHSS的预防可从促排卵周期前及促排卵周期间两个时期入手,以达未病先防之效。中医对OHSS的治疗主要为方药治疗以及针灸治疗,适用于轻、中度OHSS患者,而对于中度以上的OHSS患者需要中西医结合标本兼治,以做到已病防变。

Ovarian hyperstimulation syndrome(OHSS) is one of the most serious and common complications of assisted reproductive technology,whose incidence is increasing year by year. At present,there is still a lack of effective prevention and treatment in clinic,but Chinese medicine has unique advantages in the prevention and treatment of OHSS. The etiology and pathogenesis of OHSS have mainly three types,namely spleen-kidney deficiency and water-dampness retention,yin deficiency with yang hyperactivity and qi and blood stasis, as well as blood aspect disharmony and water retention. The prevention and treatment of OHSS in Chinese medicine can be started from both before and during ovulation induction cycles,so as to achieve the effect of preventing disease before it arises. Chinese medicine treatments of OHSS are mainly prescriptions,acupuncture and moxibustion,which are suitable for patients with mild to moderate OHSS;when it comes to above moderate OHSS, patients need to be given integrated Chinese and western medicine to treat the root and branch simultaneously,so as to control the development of existing disease.