季节性流感与气象因素相关性的系统评价

Correlation between seasonal influenza and meteorological factors:a systematic review

目的对季节性流感活动水平与气象因素之间的相关关系进行探讨。方法计算机检索PubMed、Cochrane图书馆、OVID、EBSCO、Web of Science等英文电子数据库中有关流感与气象因素相关性的文献,检索文献截至2019年5月,语种限定为英文。共纳入45篇有效文献,包括实验室和流行病学研究,并将流行病学研究的研究地点按不同气候区进行分层,提取和整理分析纳入文献的基本信息、研究的气象因素、统计方法等。结果大多数流行病学研究使用了某种类型的回归分析,温带地区流感活动与低温低湿关系显著;亚热带和热带地区流感活动与气温和湿度之间的关联较为复杂且不一致,而降雨似乎会造成热带地区流感活动水平的升高。结论温带地区寒冷干燥和热带地区潮湿多雨的环境因素与流感流行关系密切,但关于太阳辐射、风速、大气压等气象因素对流感活动影响的信息仍然有限。

Objective To explore the correlation between seasonal influenza activity level and meteorological factors.Methods A literature retrieval of papers about influenza activity and meteorological factors published by May 2019 in English electronic databases,such as Pubmed,Cochrane Library,OVID,EBSCO and Web of Science,was conducted.A total of 45 qualified literatures were included,including laboratory and epidemiological surveys.Research sites of epidemiological studies were stratified according to different climatic regions,and basic information,meteorological factors and statistical methods of the included literatures were extracted,classified and analyzed.Results Most epidemiological studies used some type of regression analysis.Influenza activity in temperate region was significantly associated with low temperature and low humidity.The correlation between influenza activity and temperature or humidity in subtropical and tropical regions were complex and inconsistent,and rainfall might increase the level of influenza activity in tropical region.Conclusion Environmental factors,such as cold and dry climate in temperate region and humid and rainy climate in tropical region,are closely related to influenza activity,but the information about the influence of meteorological factors,such as solar radiation,wind speed,and atmospheric pressure,on influenza activity is still limited.