酒精使用障碍患者脑功能磁共振成像研究进展

Research progress of brain functional magnetic resonance imaging in patients with alcohol use disorders

酒精使用障碍(alcohol use disorder,AUD)问题遍布全球,是最常见的成瘾性障碍。长期大量饮酒可造成躯体、精神及家庭社会危害,是人类重要的死亡原因之一。尽管越来越多的研究提示AUD患者大脑存在功能损伤,然而这种异常仍鲜有系统的论述。现回顾目前国内外有关AUD基于磁共振的功能影像学研究进展,总结影像学特征性表现,以期帮助临床医生较充分地了解AUD患者的功能影像学变化,有助于临床诊治工作。

Alcohol use disorder(AUD)is the most common addiction disorder worldwide.Long-term heavy drinking can cause physical,mental and family social harm,which has become one of the important causes of death.Although a growing number of studies suggest that there is functional impairment in the brain of patients with AUD,this abnormality has not been systematically discussed.This paper reviews the research progress of functional imaging studies on AUD at home and abroad based on MRI and summarizes the imaging characteristics.It is hoped that it could help clinicians fully understand the changes of functional imaging in patients with AUD and contribute to clinical diagnosis and treatment.