细胞因子在干燥综合征中作用研究进展

Research progress on the the function of cytokines in Sjogren's syndrome

机体内的免疫细胞和非免疫细胞合成及分泌的小分子多肽类因子统称为细胞因子.随着对干燥综合征(Sjogren's syndrome)的病理生理学的深入研究,发现细胞因子在干燥综合征发病及其疾病过程中起重要作用.本文介绍了各种细胞因子生物学功能,阐述了它们在干燥综合征患者血清和唾液腺中的表达情况及其与该疾病活动程度的关系.

Opypeptide agents synthesized and excreted from immunocyte or nonimmune cells are called cytokines.With the deeply study on pathophysiology of Sjogren's syndrome,we found that cytokines played an important role in the pathogenesis and progress of Sjogren's syndrome.This article reviews the biological function of cytokines and their expression in the serum and salivary glands of patients with Sjogren's syndrome.The relationship between cytokines and disease activity was also described.