载银香茅油微胶囊的合成及其抑菌性能

Synthesis of citronella oil microcapsules containing nano-Ag and its antibacterial property

为了提高香茅油的缓释和抑菌性能,通过原位聚合法制备载银香茅油微胶囊,利用香茅油和银粒子的协同作用增强抑菌效果。以香茅油(OC)为芯材,用甲基丙烯酸甲酯(MMA)、三羟甲基丙烷三丙烯酸酯(TMPTA)以及纳米银粒子(AgNP)作为组成壳材的原材料制备载银香茅油微胶囊,分别采用XRD、SEM、FTIR、TGA对不同芯壳比样品的物相、形貌、结构、热性能等进行测试表征,并进行缓释与抑菌性能测试。结果表明:载银香茅油微胶囊呈蚕豆形,有明显凹陷;随着芯壳质量比的增加,粒径增大,尺寸在2~20μm;负载银粒子的微胶囊热稳定性与缓释性能优于未负载银的微胶囊;抑菌测试表明含有香茅油的微胶囊对金黄色葡萄球菌有很好的抑菌效果,当微胶囊负载银后效果更佳,抑菌率高达99.9%。该研究为天然精油在抑菌方面的应用提供了有意义的理论参考。

In order to improve the slow release and antibacterial properties of citronella oil,citronella oil microcapsules containing nano-Ag were prepared by in-situ polymerization method,and the antibacterial effect was enhanced by the synergistic effect of citronella oil and Ag particles.Citronella oil microcapsules containing nano-Ag were prepared by using citronella oil(OC)as the core material,and adopting methyl methacrylate(MMA),trimethylolpropane triacrylate(TMPTA)and nano-Ag(AgNP)particles as shell materials.The phase,morphology,structure and thermal properties of the samples with different core-shell proportions were characterized by X-ray powder diffraction(XRD),Scanning electron microscopy(SEM),Fourier transform infrared spectroscopy(FTIR),and Thermo gravimetric analysis(TGA).Besides,slow release and antibacterial property test was conducted.The results showed that the microcapsules presented the shape of bean with obvious pits.The particle size increased from 2 to 20μm with the increase of core-shell ratio.The thermal stability and slow release property of the AG-loaded microcapsules got better than those of the microcapsules without Ag.The antibacterial test showed that the microcapsules containing citronella oil had a good antibacterial effect on staphylococcus aureus.Furthermore,the Ag-loaded microcapsules showed a better antibacterial effect with a bacteriostatic rate of 99.99%.This study provides a significant theoretical guidance for the application of natural essential oil in the antibacterial aspect.