实时直接分析高分辨质谱技术研究碳硼烷类化合物

Study of Carboranes by High Resolution Mass Spectrometry under Direct Analysis in Real Time

该文运用高分辨质谱技术对实时直接分析(Direct analysis in real time,DART)离子化条件下碳硼烷化合物的质谱行为进行了研究,对碳硼烷化合物DART高分辨质谱中所得到的同位素峰簇进行了表征与归属。研究结果表明,选取的碳硼烷化合物在DART负离子条件下均能得到较好的质谱信号,这可能与硼笼结构的“缺电性”有关。含10个B原子的碳硼烷化合物形成的离子同位素峰簇信号中,通常情况下相对丰度最高的同位素峰中含2个10B以及8个11B。将碳硼烷化合物高分辨质谱分析的精确m/z数据信息与图谱中同位素峰轮廓分析相结合,是碳硼烷化合物有效的质谱定性分析与表征策略。

In this study,high resolution mass spectrometry(HRMS)was used to study and characterize carboranes under direct analysis in real time(DART)ionization condition.Generally,good MS signals could be obtained in the determination of carboranes in negative ion DART conditions,which might possibly be the reason of boron cage with“electron-deficient”property.In the isotope peaks formed by carboranes containing 10 B atoms at high resolution DART mass spectra,the mass peak with the highest relative abundance normally contains 210B atoms and 811B atoms.Considering both the accurate high-resolution m/z data and isotope mass peaks profile analysis is an effective strategy for qualitative analysis and characterization of carboranes.