摘要
该文针对我国目前中药质量评价体系现状,总结了中药质量评价的关键科学问题,并围绕“发现”与“控制”有效成分的中药质量评价方法进行探讨。笔者结合多年中药质量分析研究工作经验,分析了中药“谱-效”关系研究、全时段等基线多波长融合指纹图谱、生物活性测定法3种质量评价与检测方法的研究内容、手段、适用范围等,为丰富、完善中药质量控制方法和中药质量标准体系的提升提供了借鉴。
In view of current situation for the quality evaluation system of traditional Chinese medicine(TCM),the key scientific problems for TCM quality evaluation are summarized.The methods for quality evaluation of TCM based on“discovery”and“control”effective ingredients are mainly discussed in this paper.Combined with the author′s years of experience in quality analysis and research of TCM,the research contents,means and application scopes of three quality evaluation and detection methods are analyzed,including“spectrum-effect”relationship research,multi-wavelength fusion fingerprint and biological activity determination,so as to provide a reference for enriching and improving the quality control methods and quality standard system of TCM.
作者
王帅
包永睿
李天娇
杨欣欣
孟宪生
WANG Shuai;BAO Yong-rui;LI Tian-jiao;YANG Xin-xin;MENG Xian-sheng(College of Pharmacy,Liaoning University of Traditional Chinese Medicine,Dalian 116600,China;Liaoning Multi-dimensional Analysis of Traditional Chinese Medicine Technical Innovation Center,Dalian 116600,China)
出处
《分析测试学报》
CAS
CSCD
北大核心
2021年第1期132-138,共7页
Journal of Instrumental Analysis
基金
辽宁省重点研发计划项目(2020JH2/10300088)
辽宁省自然科学基金项目(2019-ZD-0946,2020-MZLH-35)。
关键词
中药质量评价
“谱-效”关系研究
全时段等基线多波长覆盖融合指纹图谱
生物活性测定法
quality detection of traditional Chinese medicine
“spectrum-effect”relationship research
full-time isometric multiwavelength fusion fingerprint
bioactivity determination