培哚普利对缺血性脑卒中患者卒中相关性肺炎的影响

目的探讨缺血性脑卒中后培哚普利片对卒中相关性肺炎的影响。方法选取2017年1月至2019年1月发病>72 h的缺血性脑卒中患者,174例患者随机分成对照组(标准内科治疗)与观察组(加用培哚普利片4 mg,1次/d,共4周)。观察两组患者14 d卒中相关性肺炎发生率及第90天mRS评分。结果治疗后观察组卒中相关肺炎比例低于对照组(R<0.05);观察组患者90 d mRS评分(0~2分)低于对照组。结论培哚普利片能明显降低缺血性脑卒中患者卒中相关性肺炎发生率,且能明显改善患者神经功能。

Objective To investigate the effect of perindopril tablets on stroke-related pneumonia after ischemic stroke.Methods Patients with ischemic stroke and hypertension who were hospitalized for more than 72 hours in the Department of Neurology,Lishui Traditional Chinese Medicine Hospital and Lishui Central Hospital from January 2017 to January 2019 were selected.174 patients were randomly divided into a control group(standard medical treatment)and a treatment group(perindopril 4 mg qd for 4 weeks).The incidence of stroke-associated pneumonia at 14 days and the mRS score at 90 days were observed in the two groups.Results After treatment,the proportion of stroke-related pneumonia in the treatment group was significandy lower than that in the control group(P<0.05);the 90-day mRS score(0 to 2 points)in the treatment group was significandy lower than that in the control group.Conclusion Perindopril tablets can significandy reduce the incidence of stroke-associated pneumonia in patients with ischemic stroke and hypertension,and can significandy improve the neurological function of patients.