早期登革热患者的外周血细胞特点分析

目的分析登革热患者外周血细胞的变化,探讨其早期预测登革热的应用价值。方法选取登革热患者146例(登革热组),健康体检者100例为对照组。应用Sysmax XE2100全自动血球仪进行全血细胞计数和分类。比较两组血细胞的差异。结果登革热组患者白细胞计数(wBC)和血小板计数(PLT)相较健康体检者均降低(P<0.05),中性粒细胞计数(NE)和淋巴细胞计数(LY)低于健康对照组(P<0.05),嗜酸性粒细胞百分比(E%)低于健康对照组(P<0.05),而嗜碱性粒细胞百分比(B%)高于健康对照组,其它细胞参数差异无统计学意义(P>0.05)。结论外周血细胞的分析在登革热早期诊断和预后评估中具有临床应用价值。

Objective To analyze the change of peripheral hemogram of dengue fever patients and to assess their use and value in early diagnosis.Methods A total of 100 healthy subjects and 146 dengue patients were enrolled.Whole blood count and differential count were determined by Sysmax XE2100.The differences of blood cells between the two groups were compared.Results WBC,PLT,Neutrophil count,Lymphocyte count,Eosinophil percentage were significantly lower in patients of dengue fever,compared with the healthy subjects(P<0.05),Basophil percentage were higher in patients of dengue fever.There was no significant difference in other parameters.Conclusion Analysis of characteristics of peripheral hemogram may play a role in the early diagnosis and prognosis of dengue.