孕妇生殖道β溶血性链球菌感染与胎膜早破的关系及对母儿预后的影响

Relationship between group B Streptococcus infection in genital tract and premature rupture of membranes in pregnant women and its influences on maternal and neonatal prognosis

目的探讨孕妇生殖道β溶血性链球菌(GBS)感染与胎膜早破(PROM)的关系及对母儿预后的影响。方法回顾性分析2018年5月—2020年8月景德镇市妇幼保健院收治的50例发生PROM的孕妇为PROM组,选择同期50例未发生PROM的孕妇为对照组。记录2组孕妇的GBS阳性率和母儿结局,包括胎儿窘迫、绒毛膜羊膜炎、产褥病率、新生儿呼吸窘迫。结果PROM组孕妇出现胎儿窘迫的比例明显高于对照组(P<0.05),PROM组孕妇生殖道GBS阳性率为20.00%,明显高于对照组的2.00%(P<0.05),GBS阳性组孕妇出现胎儿窘迫、绒毛膜羊膜炎和产褥病率的比例明显高于GBS阴性组(P<0.05)。结论PROM孕妇的GBS阳性率明显升高,且GBS感染与母儿不良预后有关。

Objective To explore the relationship between group B Streptococcus(GBS)infection in genital tract and premature rupture of membranes(PROM)in pregnant women and its influences on maternal and neonatal prognosis.Methods A total of 50 PROM pregnant women who were admitted to the hospital from May 2018 to August 2020 were retrospectively analyzed and enrolled as PROM group,while another 50 pregnant women without PROM during the same period were enrolled as control group.The positive rate of GBS,and maternal and neonatal outcomes were recorded,including fetal distress,chorioamnionitis,puerperalism and neonatal respiratory distress.Results The incidence of fetal distress in PROM group was significantly higher than that in control group(P<0.05).The positive rate of GBS in genital tract of PROM group was significantly higher than of control group(20.00%vs 2.00%)(P<0.05).The incidence of fetal distress,chorioamnionitis and puerperalism in GBS positive group was significantly higher than that in GBS negative group(P<0.05).Conclusion The positive rate of GBS infection in PROM pregnant women is significantly increased.GBS infection is related to maternal and neonatal poor prognosis.