Pierre Robin序列征磁共振表现一例报道及文献复习

A case report and literature review of MRI manifestations of Pierre Robin sequence sign

Pierre Robin序列征(PRS)是一种病因复杂发病机制尚不明确的先天性发育畸形。主要表现为小下颌、腭裂、舌后坠伴气道狭窄,可导致患儿出生后呼吸及喂养困难,该病病死率较高,严重威胁新生儿的生命安全。本文患儿于孕30周左右早产且出生后即出现呼吸困难,后经抢救无数后死亡,现回顾性分析PRS胎儿磁共振表现及相关文献复习,对该病的发病机制、病因、临床诊断及治疗措施进行深入了解,提高大家对该病的认识,从而改善患儿出生后生存情况。

Pierre Robin sequence(PRS)is a congenital malformation with complex etiology and unclear pathogenesi.It is characterized by micrognathia,cleft palate,glossoptosis and airway stenosis,which can lead to difficulty in breathing and feeding after birth.The mortality of this disease is high,which seriously threatens the life safety of newborn.In this study,the infant was born prematurely at about 30 weeks of gestation and had dyspnea immediately after birth,and died after the rescue failed.In order to improve the understanding of the disease and improve the postpartum survival rate of children,we retrospectively analyzed and discussed the pathogenesis,etiology,clinical diagnosis,treatment and related literature review of fetal magnetic resonance imaging of PRS.