2019年我院门急诊麻醉药品使用情况分析

Analysis on usage of narcotic drugs in outpatient and emergency department from our hospital in 2019

目的:了解本院门急诊麻醉药品的使用情况并评价其合理性,为临床合理使用麻醉药品提供参考。方法:调取2019年本院门急诊麻醉药品处方1895张,对麻醉药品的用量、销售金额、用药频度(DDDs)、限定日费用(DDC)及药品排序比(B/A)进行统计分析。结果:2019年本院门急诊使用的麻醉药品共15个品种,其中注射剂3种,片剂10种,贴剂2种。DDDs排序居前3位的麻醉药品依次为芬太尼透皮贴(8.4 mg)、硫酸吗啡缓释片(30 mg)和芬太尼透皮贴(4.2 mg),盐酸吗啡缓释片(10 mg)的DDDs较低,三种注射剂均偏低;盐酸羟考酮缓释片(40 mg)的DDC高于其他品种,其次为盐酸吗啡缓释片(10 mg),盐酸布桂嗪片(30 mg)最低。盐酸布桂嗪片(30 mg)和硫酸吗啡片(20 mg)的B/A值大于1,硫酸吗啡缓释片(10 mg)和羟考酮缓释片(40 mg)的B/A小于1,其余品规均接近1。结论:本院门急诊麻醉药品的使用基本合理,但仍然存在不足,需要进一步加强管理。

Objective:To investigate the application status of narcotic drugs in outpatient and emergency department from our hospital and to evaluate the application rationality to provide a reference for the rational application of narcotic drugs in the clinic.Methods:1895 outpatient and emergency prescriptions with narcotic drugs during 2019 were extracted from our hospital.Statistical analysis was conducted on the utilization,consumption sum,frequency of drug use(DDDs),defined daily cost(DDC),and drug sequence ratio(B/A)of narcotic drugs.Results:During 2019,there were 15 categories of narcotic drugs used in the outpatient and emergency department of Tianjin Medical University Cancer Institute and Hospital,including 3 kinds of injections,10 kinds of tablets,and 2 kinds of transdermal patches.The top 3 narcotic drugs ranked by DDDs were fentanyl transdermal patches(8.4 mg),morphine sulfate sustained-release tablets(30 mg),and fentanyl transdermal patches(4.2 mg),respectively.The DDDs of morphine hydrochloride sustained-release tablets(10 mg)were relatively low,and all three injections were low.The DDC of oxycodone hydrochloride sustained-release tablets(40 mg)was much higher than other categories,followed by morphine hydrochloride sustained-release tablets(10 mg).The lowest was bucinnazine hydrochloride tablets(30 mg).The drug sequence ratio of bucinnazine hydrochloride tablets and morphine sulfate tablets(20 mg)were above 1.In comparison,the drug sequence ratio of morphine sulfate sustained-release tablets(10 mg)and oxycodone hydrochloride sustained-release tablets(40 mg)were lower than 1.The others were close to 1.Conclusions:The utilization of narcotic drugs in our hospital is rational on the whole,but there are still some problems,which need further efforts to strengthen the management.