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小关节超声整体评分系统在类风湿关节炎疗效评估中的应用 被引量:1

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摘要 目的分析小关节超声整体评分系统(GLOSS)在类风湿关节炎(RA)疗效评估中的应用效果。方法择取河南省南阳市西峡县人民医院2018年1月至2019年1月收治的30例RA患者为研究对象,以患者使用抗风湿药物治疗为治疗起点,在治疗起点(T_(0))、治疗后1个月(T_(1))、治疗后3个月(T_(2))、治疗后12个月(T_(3))进行疾病活动评分、C反应蛋白(CRP)与血沉(ESR)值及GLOSS检查,比较两组患者T_(0)、T_(1)、T_(2)、T_(3)期的疾病活动评分、C反应蛋白(CRP)与红细胞沉降率(ESR)值及GLOSS检查情况。结果治疗后,患者的疾病活动评分、CRP与ESR值均有下降。T_(3)期的疾病活动评分、CRP与ESR值均显著低于T_(0)期,差异显著(P<0.05);T_(1)期、T_(2)期的疾病活动评分、CRP与ESR值与T_(0)期比较无显著差异(P>0.05)。患者T_(3)期的滑膜炎GSUS评分与T_(1)期、T_(2)期、T_(3)期的滑膜炎PDUS、肌腱/腱鞘炎PDUS评分均显著低于T_(0)期,差异显著(P<0.05);患者T_(1)期、T_(2)期、T_(3)期的肌腱/腱鞘炎GSUS及骨侵蚀评分与T_(0)期比较无显著差异(P>0.05)。结论将GLOSS应用于RA的疗效评估中,能有效反映患者治疗后的组织损伤情况,为临床治疗方案提供参考依据。
出处 《临床研究》 2021年第4期82-84,共3页 Clinical Research
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