间质性肺疾病的临床特点及抗感染治疗的效果观察

Clinical Characteristics of Interstitial Lung Disease and the Effect of Anti-infective Therapy

目的在分析间质性肺疾病患者的临床特点的基础上,进一步分析评价抗感染治疗的临床效果。方法本次将我院于2017年1月至2018年1月收治的间质性肺疾病患者72例为研究对象,通过临床诊断,了解患者的具体病情特点及症状,根据具体病情特点及症状,实施有针对性的抗感染药物治疗。结果 (1)在临床疗效方面,本次72例患者,显效56例(77.78%)、有效10例(13.89%)、无效6例(8.33%),总有效率为91.67%。(2)与治疗前比较,患者治疗后的动脉血氧分压(PaO2)、一氧化碳弥散量(DLCO)以及静态肺活量(SVC)三项肺功能指标均明显提升,治疗前后数据差异具备统计学意义(P<0.05)。结论间质性肺疾病患者的临床特点较多,包括:其一,主要临床症状有气促、发热、干咳、口干、关节肿痛、胸痛及呼吸困难等;其二,X线表现为弥漫性阴影,或存在结节样间质性阴影;其三,若为早期间质性肺疾病病变,则肺内主要表现为不规则线条网格样变化,且存在囊性小气腔形成等。需根据患者的具体病情及临床特点,采取有针对性的抗感染药物进行治疗,从而提高临床治疗效果,改善患者的肺功能状态。

Objective Based on the analysis of the clinical characteristics of patients with interstitial lung disease, Further analysis and evaluation of the clinical effect of anti-infection treatment. Methods Seventy-two patients with interstitial lung disease treated in our hospital from January 2017 to January 2018 were studied, through clinical diagnosis, understand the patient’s specific characteristics and symptoms, according to the characteristics and symptoms of the disease, implement targeted anti-infective drug therapy. Results(1) In terms of clinical efficacy, this 72 patients, 56 cases were markedly effective(77.78%), 10 cases were effective(13.89%), 6 cases were invalid(8.33%), the total effective rate was 91.67%.(2) After treatment, the pulmonary function indexes of arterial partial pressure(PaO2), carbon monoxide dispersion(DLCO) and static vital capacity(SVC) were significantly improved, data difference before and after treatment was statistically significant(P<0.05). Conclusion There are many clinical features in patients with interstitial lung disease. First, the main clinical symptoms include shortness of breath, fever, dry cough, dry mouth, joint swelling and pain, chest pain and dyspnea;second, a diffuse shadow, or the presence of nodular interstitial shadows;third, if it is an early interstitial lung disease, then the lung mainly showed irregular line grid changes, and there is cystic microcavity formation and so on. According to the patient’s specific condition and clinical characteristics, taking targeted anti-infective drugs for treatment, so as to improve the clinical effect, improve the lung function of patients.