盐酸氨溴索辅助治疗慢性支气管炎的药效评价

Evaluation on the efficacy of ambroxol hydrochloride in the adjuvant treatment of chronic bronchitis

目的:评价盐酸氨溴索辅助治疗慢性支气管炎的药效。方法:2018年7月-2020年1月收治慢性支气管炎患者145例,随机分为两组。对照组应用抗生素治疗;试验组在抗生素基础上增加盐酸氨溴索辅助治疗。比较两组治疗效果。结果:试验组治疗总有效率高于对照组,差异有统计学意义(P<0.05);试验组各项症状缓解时间均短于对照组,差异有统计学意义(P<0.05);试验组1秒率(FEV1%)、第1秒用力呼气容积(FEV1)、二氧化碳分压(PaCO2)及氧分压(PaO2)等指标水平均优于对照组,差异有统计学意义(P<0.05)。结论:慢性支气管炎应用盐酸氨溴索辅助治疗,可增强临床疗效,改善患者身体功能,缩短病程。

Objective:To evaluate the efficacy of ambroxol hydrochloride in the adjuvant treatment of chronic bronchitis.Methods:From July 2018 to January 2020,145 cases of patients with chronic bronchitis were enrolled,they were randomly divided into two groups.The control group was treated with antibiotics.The experimental group increased ambroxol hydrochloride adjuvant therapy on the basis of antibiotics.The therapeutic effects between the two groups was compared.Results:The total effective rate of treatment in the experimental group was higher than that in the control group,the difference was statistically significant(P<0.05).The remission time of each symptom in the experimental group was shorter than that in the control group,the difference was statistically significant(P<0.05).The indicator levels of FEV1%,FEV1,PaCO2 and PaO2 of the experimental group were better than those of the control group,the differences were statistically significant(P<0.05).Conclusion:Ambroxol hydrochloride in the adjuvant treatment of chronic bronchitis can enhance the clinical efficacy,improve the body function of patients and shorten the course of disease.