依达拉奉联合丁苯酞治疗急性脑梗死的效果探究

Efficacy of edaravone combined with butylphthalide in the treatment of ac ute cerebral infarction

目的:探究用依达拉奉联合丁苯酞治疗急性脑梗死的效果。方法:将2017年5月至2019年6月期间北京市顺义区医院收治的150例急性脑梗死患者作为研究对象。将这些患者随机平均分为对照组和研究组。为对照组患者使用依达拉奉实施治疗。为研究组患者使用依达拉奉联合丁苯酞实施治疗。然后,比较两组患者的临床疗效、美国国立卫生研究院卒中量表(NIHSS)评分、Barthel指数评定量表评分。结果:研究组患者治疗的总有效率高于对照组患者,P<0.05。治疗前,两组患者的NIHSS评分相比,P>0.05。治疗的1周、2周及1个月后,研究组患者的NIHSS评分均低于对照组患者,P<0.05。治疗前,两组患者的Barthel指数评定量表评分相比,P>0.05。治疗1周、2周及1个月后,研究组患者的Barthel指数评定量表评分均高于对照组患者,P<0.05。结论:用依达拉奉联合丁苯酞治疗急性脑梗死的效果显著,可改善患者的神经功能,提高其日常生活自理能力。

Objective:To explore the effect of edaravone combined with butylphthalide in the treatment of acute cerebral infarction.METHODS:A total of 150 patients with acute cerebral infarction admitted to Shunyi District Hospital of Beijing from May 2017 to June 2019 were selected as the research subjects.These patients were randomly divided into control group and study group on average.Control group was treated with edaravone.Patients in the study group were treated with edaravone combined with butylphthalide.Then,clinical efficacy,National Institutes of Health Stroke Scale(NIHSS)scores and Barthel Index Rating Scale scores were compared between the two groups.Results:The total effective rate of the study group was higher than that of the control group(P<0.05).Before treatment,the NIHSS scores of patients in the two groups were compared with P>0.05.After 1 week,2 weeks and 1 month of treatment,the NIHSS scores of the study group were lower than those of the control group(P<0.05).Before treatment,the score of Barthel index rating scale of patients in the two groups was compared with that of P>0.05.After 1 week,2 weeks and 1 month of treatment,the scores of Barthel Index Scale in the study group were all higher than those in the control group(P<0.05).Conclusion:Edaravone combined with butylphthalide in the treatment of acute cerebral infarction has a significant effect,can improve the neurological function of patients,improve their self-care ability in daily life.