摘要
急性白血病是儿童非实体肿瘤的主要类型。研究显示长链非编码RNA在血液系统恶性肿瘤发病过程中发挥重要作用,并可作为白血病患者诊断、预后判断和疗效监测的生物标志物。现主要对长链非编码RNA在儿童急性白血病发生、发展中的作用进行简要综述。
Acute leukemia marks the main type of non-solid cancer in children.Studies have proved that long non-coding RNA plays important roles in the pathogenesis of hematological malignancies and can be applied as a biomarker for diagnosis,prognosis and efficacy monitoring of leukemia patients.This article briefly reviews the roles of long non-coding RNA in the tumorigenesis and progression of childhood acute leukemia.
作者
肖楠
李占峰
李锐
姚建新
潘志尧
姚志峰
Xiao Nan;Li Zhanfeng;Li Rui;Yao Jianxin;Pan Zhiyao;Yao Zhifeng(Department of Radiation Oncology,Center for Oncological Medicine,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,China;Faculty of Medical Technology,Nanjing Health School,Jiangsu United Vocational and Technical College,Nanjing 210038,China;Leukemia Treatment Center,Blood Disease Hospital,Chinese Academy of Medical Sciences,Tianjin 300020,China;Faculty of Biochemistry,School of Basic Medical Sciences,Zhejiang University,Hangzhou 310058,China)
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2021年第3期231-235,共5页
Chinese Journal of Applied Clinical Pediatrics
