虚拟支气管镜导航结合支气管内超声引导下经支气管肺活检对孤立性肺结节的实用性

Usefulness of virtual bronchoscopic navigation combined with endobronchial ultrasound guided transbronchial lung biopsy for solitary pulmonary nodules

目的评估虚拟支气管镜导航(VBN)结合支气管内超声(EBUS)指导的经支气管肺活检对孤立性肺结节(SPN)的诊断实用性。方法选取2018年1月到2020年1月在我院接受单纯EBUS引导或VBN+EBUS引导下TBLB治疗的SPN患者164例。将患者随机分为EBUS组和VBN+EBUS组。比较两组的诊断率和检查时间。结果VBN+EBUS组和EBUS组之间的诊断率差异有显著性(P=0.015)。当分析直径小于20 mm的病变时,VBN+EBUS组的诊断率高于EBUS组(P=0.017)。VBN+EBUS组的病变定位时间少于EBUS组(P=0.015)。但两组的总检查时间差异无统计学意义(P=0.236)。两组的并发症发生率差异无统计学意义。结论VBN可以缩短定位时间,是一种安全有效的肺结节技术。

Objective To evaluate the diagnostic utility of virtual bronchoscopic navigation(VBN) combined with endobronchial ultrasound(EBUS) guided transbronchial lung biopsy for solitary pulmonary nodules(SPN). Methods A total of 164 patients with suspected SPN who underwent transbronchial lung biopsy were evaluated. The patients were randomly divided into the EBUS group and the virtual bronchoscopic navigation combined with endobronchial ultrasound(VBN+EBUS) group. The diagnostic yield and examination time were compared. Results There was significant difference in the diagnostic yield between the VBN+EBUS group and the EBUS group ( P = 0. 015). When the lesions less than 20 mm were analyzed,the diagnostic yield was higher in the VBN + EBUS group than in the EBUS group( P = 0. 017). The time for positioning lesions in the VBN + EBUS group was less than that in the EBUS group( P = 0. 015). But the total examination time was not significantly different between the two groups( P = 0. 236). The incidence of complications did not differ between the two groups. Conclusion In conclusion,VBN can shorten the positioning time and it is a safe and effective technique for pulmonary nodules.