摘要
The Holy Grail to address the clinical grand challenge of human limb loss is to develop innovative strategies to regrow the amputated limb.The remarkable advances in the scientific understanding of regeneration,stem cell science,material science and engineering,physics and novel surgical approaches in the past few decades have provided a regenerative tool box to face this grand challenge and address the limitations of human wound healing.Here we discuss the convergence approach put forward by the field of Regenerative Engineering to use the regenerative tool box to design and develop novel translational strategies to limb regeneration.
基金
This work was supported by the NIH Director’s Pioneer Award,1DP1AR068147,R21-AR062771,R01-AR063698
funding from Raymond and Beverly Sackler Center for Biomedical,Biological,Physical and Engineering Sciences.C.T.L.was the recipient of the Presidential Faculty Fellowship Award from President William Clinton and the Presidential Award for Excellence in Science,Mathematics,and Engineering Mentorship and the National Medial of Technology and Innovation from President Barack Obama.
