知觉压力与轻度认知障碍

Perceived stress and mild cognitive impairment

轻度认知障碍(mild cognitive impairment,MCI)是介于正常衰老与痴呆之间的一种过渡状态,是延缓认知衰退的最佳干预窗口期。知觉压力作为影响认知功能且可调节的危险因素之一,通过引发下丘脑-垂体-肾上腺轴功能失调及心理障碍,显著增加了认知障碍的发病风险,因而知觉压力管理逐渐成为认知障碍非药物干预技术研究和实践的新热点。文章就MCI人群知觉压力的现状,知觉压力与认知功能的关系,以及MCI个体知觉压力评估技术等方面进行梳理,并以压力归因模型为基础,对知觉压力的相关影响因素进行综述,深入剖析了知觉压力干预方案对认知功能管理的作用机制与实践启示,以期为开拓MCI人群认知功能管理的新路径提供理论参考与借鉴。

Mild cognitive impairment is a transitional state between normal aging and dementia,which is the best intervention window to delay cognitive decline.As one of the adjustable risk factors affecting cognitive function,perceived stress significantly increases the risk of cognitive impairment by causing hypothalamic-pituitary-adrenal axis dysfunction and psychological disorders.Therefore,perceived stress management will become a new hot spot in the research and practice of non-drug intervention techniques for cognitive impairment.This paper reviews the current situation of perceived stress in MCI population,the relationship between perceived stress and cognitive function,and the evaluation techniques of MCI individual perceived stress.Further more,this paper summarizes the relevant influencing factors of perceived stress based on stress attribution model,and comments on the action mechanism and practical enlightenment of perceived stress intervention program on cognitive function management,in order to provide theoretical reference for cognitive function management of MCI population.