源自汉代经典名方的已上市中成药及日本汉方药与古代医籍剂量对比分析

Comparative Analysis on Drug Dosage of Listed Chinese Patent Medicines,Japanese Kampo Medicines and Ancient Medical Records Derived from Classical Prescriptions of Han Dynasty

对源自汉代经典名方的已上市中成药、日本汉方药处方剂量及日服饮片量与古代医籍、《方剂学》教材进行对比,分析汉代经典名方的处方剂量在已上市药品中的换算规律,为古代经典名方的剂量换算研究提供参考。共梳理了15个汉代经典名方在已上市中成药及日本汉方药中的处方剂量,换算结果为一两为0.2~3.8 g。已上市中成药丸散剂一两换算为0.2~0.9 g;颗粒剂、合剂一两换算为1.0~3.8 g。日本汉方药大多按一两不超过1.5 g进行换算。已上市中成药丸散剂日服饮片量为9~18 g;颗粒剂或合剂日服饮片量为45~90 g。日本汉方药均为颗粒剂,其日服生药量大多为10~30 g。

In this paper,by comparing the prescription dose and daily dose of listed Chinese patent medicines and Japanese Kampo medicines derived from classical prescriptions of Han dynasty with ancient medical books and prescription textbooks,the conversion rule of the drug dosage of classical prescriptions of Han dynasty in listed drugs is analyzed,which provides reference for the conversion study of ancient classical prescriptions.The prescription doses of the listed Chinese patent medicines and Japanese Kampo medicines derived from 15 classic prescriptions of Han dynasty are sorted out,1 Liang is converted to 0.2-3.8 g.For the listed Chinese patent medicines which in the form of pill or powder,1 Liang is converted to 0.2-0.9 g and 1 Liang is converted to 1.0-3.8 g when the dosage form is granule or mixture.For Japanese Kampo medicines,1 Liang is converted to no more than 1.5 g.For listed Chinese patent medicines,the daily doses of pills or powders are 9-18 g,and those of granules or mixtures are 45-90 g.The Japanese Kampo medicines are all granules,and the daily doses are mostly 10-30 g.