子宫内膜异位症致疼痛的发生机制及治疗方法研究进展

Research progress on the mechanism and treatment of pain caused by endometriosis

子宫内膜异位症常发生于已婚育龄妇女,发病率为5%~10%。其临床症状为不同形式的疼痛,而目前对于其疼痛的发生机制了解较少,主要和神经生长因子、神经纤维、炎症反应等相关。对子宫内膜异位症所致疼痛患者进行针对性的治疗和护理有助于提升其生活质量。目前的治疗方式主要有手术、药物、中医治疗,但都存在一定程度的局限性,包括反复发作、副作用、费用高等。因此,有必要对子宫内膜异位症发病机制、治疗方式进行更深层次的研究,以期找到并制定更优化的治疗方案,为患者减轻痛苦。本文通过查阅国内外的相关文献报道,特对子宫内膜异位症致疼痛的发生机制及其治疗措施进行了综述,希望可以为相关医护人员及患者提供参考,改善子宫内膜异位症致疼痛患者的疼痛状况。

The endometriosis often affects married women of childbearing age,and the incidence rate is 5%-10%.Patients with endometriosis exhibited different forms of pain in clinic.At present,the mechanism of pain remains unclear,mainly related to nerve growth factor,nerve fiber and inflammatory reaction.Targeted treatment and nursing care is helpful to improve the quality of life of patients with pain caused by endometriosis.The main treatment methods included surgery,medicine and traditional Chinese medicine,which showed some limitations,including repeated attacks,side effects and high cost.Therefore,it is necessary to further study the pathogenesis and treatment of endometriosis to find and formulate a more optimized treatment plan to relieve the pain of patients.In this paper,the mechanism of pain caused by endometriosis and its treatment measures are reviewed by consulting relevant literature reports at home and abroad,hoping to provide a reference for medical staff to relieve the pain of patients with pain caused by endometriosis.