闭合式鼻咽冲洗法在鼻咽癌放疗患者中的应用效果和安全性观察

Observation on the application efficacy and safety of closed nasopharynx irrigation in patients with nasopharyngeal carcinoma undergoing radiotherapy

目的探究闭合式鼻咽冲洗法对鼻咽癌放疗患者的应用效果及安全性。方法选取2018年1月至2020年1月阳春市人民医院耳鼻喉科收治的60例鼻咽癌患者,按照随机数字表法分为对照组与研究组各30例。对照组患者实施开放式鼻咽冲洗,研究组患者实施闭合式鼻咽冲洗法。比较两组患者鼻咽黏膜反应程度、鼻咽分泌物黏稠度、呼吸道反应、治疗舒适度、满意度及生活质量。结果研究组鼻咽分泌物黏稠度低于对照组,差异有统计学意义(P<0.05),两组鼻咽黏膜反应程度比较,差异有统计学意义(P<05);研究组呼吸道反应发生率低于对照组,差异有统计学意义(P<0.05);研究组治疗舒适度及满意度均显著高于对照组(P<0.05);研究组患者的生活质量显著高于对照组,差异有统计学意义(P<0.05)。结论对于行放疗治疗的鼻咽癌患者,闭合式鼻咽冲洗法有较好的冲洗效果,且有较好的安全性,因此可行应用及推广。

Objective To investigate the application efficacy and safety of closed nasopharynx irrigation in patients with nasopharyngeal carcinoma undergoing radiotherapy.Methods A total of 60 patients with nasopharyngeal carcinoma admitted to the department of otorhinolaryngology of Yangchun People's Hospital from January 2018 to January 2020 were selected and they were divided into the control group(n=30)and the study group(n=30)according to the random number table method.The patients in the control group were treated with nasopharynx irrigation in an open way,while those in the study group were treated with closed nasopharynx irrigation.The degree of nasopharynx mucosa reaction and the viscosity of nasopharynx secretion were compared between the two groups of patients,and the respiratory tract reaction,treatment comfort and satisfaction were counted and compared between the two groups.Meanwhile,the QoL of patient was counted.Results The viscosity of nasopharynx secretion in the study group was lower than that in the control group,with statistically significant difference(P<0.05).There was statistically significant difference in the degree of rhinitis mucosa reaction between the two groups(P<0.05).The incidence of respiratory tract reaction in the study group was lower than that in the control group,with statistically significant difference(P<0.05).The treatment comfort and satisfaction of patients in the study group were significantly higher than those in the control group(P<0.05).The QoL in the study group was significantly higher than that in the control group,with statistically significant difference(P<0.05).Conclusion For patients with nasopharyngeal carcinoma treated by radiotherapy,the closed nasopharyngeal irrigation method has better irrigative efficacy and higher safety,so it is feasible to be applied and promoted.