肺炎支原体肺炎合并胸腔积液相关因素分析

Analysis of related factors of mycoplasma pneumoniae pneumonia complicated with pleural effusion

目的探讨儿童肺炎支原体肺炎(MPP)合并胸腔积液的相关影响因素。方法将386例MMP患儿根据影像学检查结果分为观察组(合并胸腔积液)168例和对照组(无胸腔积液)218例。分析MPP合并胸腔积液的危险因素;观察2组间实验室检查各项指标变化。结果观察组年龄高于对照组,热程、住院时间、大环内酯类使用时间长于对照组,糖皮质激素使用例数多于对照组,差异有统计学意义(P<0.05)。观察组白细胞(WBC)计数、中性粒细胞(N)百分比、C反应蛋白(CRP)、红细胞沉降率(ESR)、降钙素原(PCT)、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)均高于对照组,血清总蛋白(TP)、白蛋白(AP)均低于对照组,差异有统计学意义(P<0.05)。ESR、PCT及TP水平是MPP合并胸腔积液的独立危险因素(P<0.05)。结论儿童MPP合并胸腔积液具有多种相关影响因素,年龄增加、ESR和PCT升高、TP降低提示患儿胸腔积液发生风险增加。

Objective To investigate the related factors of mycoplasma pneumoniae pneumonia(MPP)complicated with pleural effusion in children.Methods A total of 386 children with MMP were divided into observation group(complicated with pleural effusion,n=168)and control group(without pleural effusion,n=218)according to the imaging results.The risk factors of MPP combined with pleural effusion were analyzed.The changes of laboratory examination indexes between the two groups were observed.Results The age of the observation group was significantly higher,the heat course,hospitalization time,macrolides use time were significantly longer,and the number of glucocorticoid use cases was significantly more than that of the control group(P<0.05).White blood cells(WBC)count,neutrophil percentage(N),C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),calcitonin(PCT)and immunoglobulin A(IgA),immunoglobulin G(IgG)were significantly higher than that of control group,serum total protein(TP),albumin(AP)in the observation group were significantly lower than those in the control group(P<0.05).ESR,PCT and TP levels were independent risk factors for MPP complicated with pleural effusion(P<0.05).Conclusion MPP combined with pleural effusion in children has a variety of related influencing factors,and the increase of age,the increase of ESR and PCT,and the decrease of TP indicate the increased risk of pleural effusion in children.