碘染色色素内镜鉴别诊断食管早癌与异型增生的临床价值分析

Clinical Value of Iodine Staining Chromoendoscopy in Differential Diagnosis of Early Esophageal Cancer and Dysplasia

目的探讨碘染色色素内镜在鉴别诊断食管早癌与异型增生中的临床应用。方法选取120例疑似食管癌病变患者,对所有患者行病理学检查和碘染色检查,分析病理检查结果及碘染色检查结果。结果病理诊断结果食管早癌27例,慢性炎症48例,异型增生45例(包括轻度17例,中度19例,重度9例),食管早癌碘染色表现主要为不染色占88.89%,轻度、中度、重度异型增生碘染色表现主要为浅染色和不染色,各占88.24%、78.95%、77.78%;碘染色后阳性总检出率为97.22%,高于碘染色前阳性总检出率为51.39%(P<0.05)。结论食管早癌碘染色主要表现为不染色,异型增生碘染色主要表现为浅染色和不染色,碘染色色素内镜在诊断食管早癌与异型增生中临床价值明显。

Objective To explore the clinical application of iodine staining chromoendoscopy in differential diagnosis of early esophageal cancer and dysplasia.Methods From July 2015 to August 2019,120 patients with suspected esophageal cancer lesions were selected.All patients were examined by pathology and iodine staining,and the results of pathological examination and iodine staining were analyzed.Results Pathological diagnosis:27 cases of early esophageal cancer,48 cases of chronic inflammation,45 cases of dysplasia(including mild 17 cases,moderate 19 cases,severe 9 cases).Early esophageal cancer with iodine staining is mainly unstained,accounted for 88.89%,and mild,moderate,and severe dysplasia iodine staining is mainly light and unstained,each accounting for 88.24%,78.95%,77.78%.The total positive detection rate after iodine staining was 97.22%higher than that before iodine staining(51.39%)(P<0.05).Conclusion Iodine staining of early esophageal cancer is mainly non-staining,dysplasia iodine staining is mainly light and non-staining,and iodine staining chromoendoscopy has obvious clinical value in the diagnosis of early esophageal cancer and dysplasia.