小儿湿咳方联合穴位敷贴治疗儿童慢性湿性咳嗽临床研究

Clinical Study on Children with Chronic Wet Cough Treated by Xiao’er Shike Formula Combined with Acupoint Application

【目的】观察小儿湿咳方联合穴位敷贴治疗儿童慢性湿性咳嗽的临床疗效。【方法】将120例1~14岁慢性湿性咳嗽患儿随机分为观察组(中药+敷贴组)和对照组(中药组),每组各60例。对照组给予中药小儿湿咳方内服治疗,观察组给予中药小儿湿咳方联合穴位贴敷治疗,疗程为2周。观察2组患儿治疗前后咳嗽症状评分、咳嗽视觉模拟量表(VAS)评分和中医证候评分的变化情况,并评价2组患儿的临床疗效。【结果】(1)治疗2周后,观察组的总有效率为93.3%(56/60),对照组为78.3%(47/60),观察组的临床疗效明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗1周和2周后,2组患儿的咳嗽症状评分和VAS评分均较治疗前明显降低(P<0.001),且随治疗时间的延长,观察组的咳嗽症状评分和VAS评分的下降幅度均明显大于对照组,差异均有统计学意义(P<0.001)。(3)治疗2周后,观察组在改善流涕、喉中有痰、食欲等中医证候方面的疗效优于对照组,差异均有统计学意义(P<0.05)。【结论】中药小儿湿咳方联合穴位敷贴治疗儿童慢性湿性咳嗽具有较好的临床疗效,其疗效优于单纯中药治疗。

Objective To observe the clinical effect of Xiao’er Shike Formula combined with acupoint application for the treatment of children with chronic wet cough.Methods A total of 120 children aged 1-14 years with chronic wet cough were randomly divided into observation group and control group,with 60 cases in each group.The control group was given oral use of Xiao’er Shike Formula,and the observation group was given Xiao’er Shike Formula combined with acupoint application.The treatment course for the two groups lasted for 2 weeks.Before and after treatment,cough symptom scores,visual analogue scale(VAS)cough scores,and traditional Chinese medicine(TCM)syndrome scores of children in the two groups were observed.And after treatment,the clinical efficacy in the two groups was evaluated.Results(1)After treatment for 2 weeks,the total effective rate of the observation group was 93.3%(56/60),and that of the control group was 78.3%(47/60).The intergroup comparison showed that the clinical efficacy of the observation group was superior to that of the control group,and the difference between the two groups was statistically significant(P<0.05).(2)After treatment for one and 2 weeks,cough symptom scores and VAS cough scores in the two groups were obviously decreased in comparison with those before treatment(P<0.001),and with the prolongation of the medication time,the decrease degree of cough symptoms scores and VAS cough scores in the observation group was superior to that in the control group,the difference between the two groups being statistically significant(P<0.001).(3)After treatment for 2 weeks,the observation group had stronger effect on relieving the TCM symptoms of runny nose,sputum in the throat and appetite than the control group,and the difference between the two groups was statistically significant(P<0.05).Conclusion Chinese herbal medicine Xiao’er Shike Formula combined with acupoint application exerts stronger effect for the treatment of children with chronic wet cough than Chinese herbal medicine Xiao’er Shike Formula alone.