血清淀粉酶、C-反应蛋白、白细胞联合检测在诊断急性胰腺炎中的应用价值

Application value of combined determination of serum amylase,C-reactive protein and leukocyte in diagnosis of acute pancreatitis

目的:探讨血清淀粉酶(AMY)、C-反应蛋白(CRP)、白细胞(WBC)联合检测在诊断急性胰腺炎(AP)中的应用价值。方法:将2018年4月至2020年5月期间云县人民医院收治的140例急腹症患者和同期在该院接受门诊体检的70例体检者作为研究对象。将病情被诊断为AP的68例急腹症患者作为AP组,将病情被诊断为其他疾病的72例急腹症患者作为非AP组,将70例体检者作为对照组。对三组研究对象均进行血清AMY、CRP、WBC联合检测。然后,比较三组研究对象的检测结果。结果:AP组患者和非AP组患者AMY的水平、CRP的水平和WBC的水平均高于对照组体检者,P<0.05。AP组患者AMY的水平高于非AP组患者,P<0.05。重症急性胰腺炎(SAP)患者CRP的水平和WBC的水平均高于轻症急性胰腺炎(MAP)患者,P<0.05。结论:血清AMY、CRP、WBC联合检测在诊断AP中具有较高的应用价值。

Objective:To explore the application value of serum amylase(AMY),C-reactive protein(CRP)and white blood cell(WBC)combined detection in the diagnosis of acute pancreatitis(AP).METHODS:A total of 140 patients with acute abdomen admitted to Yunxian People’s Hospital from April 2018 to May 2020 and 70 patients who underwent outpatient physical examination in the hospital during the same period were selected as the research subjects.Sixty-eight patients with acute abdomen diagnosed as AP were selected as the AP group,72 patients with acute abdomen diagnosed as other diseases were selected as the non-AP group,and 70 patients with physical examination were selected as the control group.Serum AMY,CRP and WBC were detected in all three groups.Then,the test results of the three groups of subjects were compared.RESULTS:The levels of AMY,CRP and WBC in AP group and non-AP group were higher than those in control group(P<0.05).The level of AMY in AP group was higher than that in non-AP group(P<0.05).The levels of CRP and WBC in severe acute pancreatitis(SAP)patients were higher than those in mild acute pancreatitis(MAP)patients(P<0.05).Conclusion:The combined detection of AMY,CRP and WBC in serum has high application value in the diagnosis of AP.