红细胞分布宽度对社区获得性肺炎病情严重程度及预后的预测价值

Value of red cell distribution width in predicting the severity and prognosis of community acquired pneumonia

目的探讨红细胞分布宽度(RDW)对老年社区获得性肺炎(CAP)患者病情严重程度及预后的预测价值。方法将91例老年CAP患者分为普通组(n=71)和重症组(n=20)。比较2组降钙素原(PCT)、C反应蛋白(CRP)、RDW水平;多因素回归分析确定老年CAP患者死亡的高危因素,并绘制受试者工作特征(ROC)曲线;评估RDW对老年CAP患者死亡的预测价值。结果重症组RDW、CRP、PCT水平均高于普通组,差异有统计学意义(P<0.05)。RDW是老年CAP患者死亡的危险因素。老年CAP患者死亡的RDW曲线下面积(AUC)为0.754,敏感度为75.00%,特异度为70.89%。结论RDW对评估老年CAP患者病情严重程度及预后具有预测价值。

Objective To investigate the predictive value of red blood cell distribution width(RDW)in the severity and prognosis of elderly patients with community-acquired pneumonia(CAP).Methods A total of 91 elderly patients with CAP were divided into common group(n=71)and the severe group(n=20).The levels of procalcitonin(PCT),C-reactive protein(CRP)and RDW were compared between the two groups;the risk factors of death in elderly patients with CAP were analysed by multivariate regression analysis,and the Receiver Operating characteristic(ROC)curve was drawn;the predictive value of RDW for death in elderly patients with CAP was evaluated.Results The levels of RDW,CRP and PCT in the severe group were significantly higher than those in the common group(P<0.05).RDW was the high risk factor of mortality in elderly patients with CAP.The area under the curve(AUC)of RDW in predicting death of elderly patients with CAP was 0.754,the sensitivity was 75.00%,and the specificity was 70.89%.Conclusion RDW has predictive value in evaluating the severity and prognosis of elderly patients with CAP.