不同方法应用于妊娠合并高血压患者临床治疗的价值分析

Analysis of the Value of Different Methods in Clinical Treatment of Patients with Pregnancy Complicated with Hypertension

目的不同方法应用于妊娠合并高血压患者临床治疗的价值分析。方法方便选取该院于2019年1—6月时段内收治的妊娠合并高血压患者150例为对象,根据随机抓阄法+单双床号法划分为对照组与治疗组,每组75例患者。对照组院内疗法为拜新同联合氢氯噻嗪方案,治疗组院内疗法为拜新同联合盐酸拉贝洛尔方案,对比两组治疗前后血压水平,参考GQOLI-74评估两组治疗后生活质量评分以及不良反应发生率。结果治疗后,治疗组患者的舒张压(62.12±6.55)mmHg、收缩压(90.23±10.11)mmHg均低于对照组的(80.05±5.79)mmHg、(112.22±11.01)mmHg,差异有统计学意义(P<0.05)。治疗组的GQOLI-74评分中心理功能(37.87±3.32)分、躯体功能(37.65±4.53)分、物质生活状态(31.75±4.42)分、社会功能(37.09±3.97)分,均高于对照组的(31.12±2.46)分、(32.13±3.02)分、(25.57±5.24)分、(32.30±2.41)分,差异有统计学意义(t=17.762、12.740、14.147、8.781、7.807、8.932,P<0.05);治疗组的不良反应发生率为6.67%低于对照组的17.33%,差异有统计学意义(χ^(2)=4.040,P<0.05)。结论妊娠合并高血压患者临床采取拜新同联合盐酸拉贝洛尔疗法,可以有效降低血压,优化患者的生活质量,且不良反应较少,可以保证患者的治疗安全性。

Objective To analyze the value of different methods in clinical treatment of patients with pregnancy complicated with hypertension.Methods 150 cases of hypertensive patients with pregnancy who were admitted to the hospital from January to June 2019 were conveniently selected as subjects.According to the random lottery method+single double bed number method,they were divided into the control group and the treatment group,75 patients each group;the control group was hospitalized with Baixintong combined with hydrochlorothiazide regimen,and the treatment group was with Baixintong combined with labetalol hydrochloride regimen.The blood pressure levels before and after treatment were compared between the two groups and GQOLI-74 was used to evaluate the two groups'treatment post quality of life score and incidence of adverse reactions.Results After treatment,the diastolic blood pressure(62.12±6.55)mmHg and systolic blood pressure(90.23±10.11)mmHg of the treatment group were lower than those of the control group(80.05±5.79)mmHg and(112.22±11.01)mmHg.The difference was statistically significant(P<0.05).In the GQOLI-74 score of the treatment group,the scores of psychological function(37.87±3.32)points,physical function(37.65±4.53)points,material life(31.75±4.42)points,and social function(37.09±3.97)points were higher than those of the control group(31.12±2.46)points,(32.13±3.02)points,(25.57±5.24)points,(32.30±2.41)points,the difference were statistically significant(t=17.762,12.740,14.147,8.781,7.807,8.932,P<0.05);the adverse reaction rate of the treatment group was 6.67%lower than that of the control group 17.33%,the difference was statistically significant(χ^(2)=4.040,P<0.05).Conclusion The clinical use of Bexintong combined with Lanolol hydrochloride in pregnancy with hypertension can effectively reduce blood pressure,optimize the patient's quality of life,and have fewer adverse reactions,and can ensure the safety of treatment for patients.