瘘管挂线术联合孕三烯酮治疗肛瘘合并子宫内膜异位症的疗效观察

Fistula-Thread-drawing Combined with Gestrinone in the Treatment of Anal Fistula Complicated with Endometriosis:Effect Observation

为观察瘘管挂线术联合孕三烯酮治疗肛瘘合并子宫内膜异位症的临床疗效,将肛瘘合并子宫内膜异位症患者30例随机分为观察组和对照组,每组15例。观察组患者采用瘘管挂线术联合孕三烯酮进行治疗,对照组患者采用瘘管挂线术联合醋酸甲孕酮进行治疗,比较2组患者的疗效、治疗前后激素水平变化及不良反应发生情况。结果显示,观察组患者总有效率高于对照组(P <0.05);在治疗后激素水平变化方面,观察组患者的促卵泡生成激素、雌二醇与孕酮均低于对照组,促黄体生成素高于对照组,比较差异有统计学意义(P <0.05);观察组患者不良反应发生率低于对照组(P <0.05)。结果表明,瘘管挂线术联合孕三烯酮治疗肛瘘合并子宫内膜异位症具有显著疗效,具有推广价值。

This study was to investigate the clinical effect of fistul-thread-drawing combined with gestrinone in the treatment of anal fistula complicated with endometriosis(EMS),randomly divided 30 patients with fistula anal complicated with EMS into observation group(15 cases,adopted fistula-thread-drawing combined with gestrinone)and control group(15 cases,fistula-thread-drawing combined with medroxyprogesterone acetate);then,compared both groups’ effect,the hormone levels’ change before and after treatment,as well as unward reaction incidence.As results,the total effective rate of observation group was higher than that of control group(P <0.05);after treatment,in observation group the levels of folliclestimulating hormone(FSH),estradiol,and progestin,and the levels of luteinizing hormone-releasing hormone were respectively lower and higher than in control group(all,P <0.05);more than,the unward reaction incidence of observation group was lower than that of control group(P <0.05).Results show that the therapy used in observation group in the treatment of EMS complicated with anal fistula has significant effect.It has popularization value.