自我效能在肝癌术后患者恐惧疾病进展与焦虑抑郁间的中介效应

Mediating effect analysis of self-efficacy in the relationship between fear of progression,and anxiety and depression among liver cancer patients

目的探讨肝癌术后患者自我效能感与恐惧疾病进展及焦虑抑郁的关系,并分析自我效能在恐惧疾病进展与焦虑抑郁间的中介效应。方法采用一般资料调查表、恐惧疾病进展量表、一般自我效能感量表、医院焦虑抑郁量表对广州市某三级甲等肿瘤医院175例原发性肝癌术后患者进行调查分析。结果肝癌术后患者自我效能总分为(2.54±0.65)分,恐惧疾病进展得分为(36.01±10.86)分,焦虑抑郁得分为(16.47±7.59)分;自我效能与恐惧疾病进展、焦虑抑郁均呈显著负相关(r_(1)=-0.385,P_(1)<0.01;r_(2)=-0.389,P_(2)<0.01);恐惧疾病进展与焦虑抑郁呈显著正相关(r=0.555,P<0.01);自我效能在肝癌术后患者恐惧疾病进展和焦虑抑郁关系中起部分中介作用,中介效应占总效应比例为16%。结论恐惧疾病进展对肝癌术后患者焦虑抑郁有直接预测作用,自我效能在肝癌术后患者恐惧疾病进展与焦虑抑郁间起部分中介作用,提高肝癌术后患者的自我效能感是降低患者焦虑抑郁的有效途径之一。

Objective To examine the potential mediating effect of self-efficacy on fear of progression(FoP)and anxiety and depression in liver cancer patients.Methods Totally,175 liver cancer patients from a 3A-level cancer hospital in Guangzhou were investigated with the general information questionnaire,Fear of Progression Questionnaire Short Form(FoP-Q-SF),General Self-Efficacy Scale(GSES),and Hospital Anxiety and Depression Scale(HADS).Results Self-efficacy score of patients with liver cancer was(2.54±0.65).The total score of FoP was(36.01±10.86),and the score of anxiety and depression was(16.47±7.59).There was a significantly negative correlation between the FoP,anxiety and depression and self-efficacy(r_(1)=-0.385,P_(1)<0.01 and r_(2)=-0.389,P_(2)<0.01).The level of fear disease progression was positively correlated with the average level of anxiety and depression(r=0.555,P<0.01).Self-efficacy has some mediating effect between the FoP and anxiety and depression,which accounts for 16%of the total effect.Conclusion The level of fear disease progression is an obvious signal of liver cancer patients'anxiety and depression.Self-efficacy plays a mediating role between the FoP and anxiety and depression in liver cancer patients.Improving self-efficacy is an effective way of reducing those patients'anxiety and depression.