膝关节牵引器治疗膝骨性关节炎50例

Clinical Study on the Treatment for Knee Osteoarthritis by Knee Traction Device

目的:探究本院自制膝关节牵引器治疗膝骨性关节炎的临床研究效果。方法:选取2019年5月至2020年5月本院收治的膝骨性关节炎患者100例,按照随机数字表简单随机分为膝关节牵引器组与手法牵引组(各50例)。于3个月后观察两组患者疼痛程度、膝关节功能、生活质量、TNF-α和IL-1水平及疗效差异。结果:重复测量结果显示:两组患者治疗前后VAS评分、JOA评分、AIMS2-SF评分,TNF-α和IL-1水平在时点、时点与组别交互间比较差异均有统计学意义(P<0.05),简单效应LSD-t成对比较结果显示,从时点角度分析,两组患者治疗后VAS评分、TNF-α,IL-1水平均显著低于治疗前,JOA评分及AIMS2-SF评分均显著高于治疗前,差异有统计学意义(P<0.05);组间方面,治疗前两组患者VAS评分、JOA评分及AIMS2-SF评分,TNF-α和IL-1水平比较,差异无统计学意义(P>0.05),治疗后膝关节牵引器组VAS评分、TNF-α和IL-1水平明显低于手法牵引组,JOA评分和AIMS2-SF评分明显高于手法牵引组,差异有统计学意义(P<0.05)。等级秩和检验结果显示:两组整体疗效差异无统计学意义(P>0.05),但疗效总有效例数膝关节牵引器组高于手法牵引组,差异有统计学意义(P<0.05)。结论:膝关节牵引器用于临床治疗膝骨性关节炎疗效明显,能有效缓解患者疼痛程度,降低TNF-α和IL-4水平,促进膝关节功能恢复,提高患者生活质量,值得临床推广应用。

Objective:To explore the clinical efficacy of self-made knee traction device in the treatment of knee osteoarthritis.Methods:100 patients with knee osteoarthritis were selected from May 2019 to May 2020.According to the random number table,it was divided into knee traction group and manual traction group with 50 cases in each.The pain degree,knee function,quality of life,TNF-α,IL-1 level and curative efficacy of the two groups were observed after three months.Results:The results of repeated measurements showed that the VAS score,JOA score,AIMS2-SF score and TNF-α,IL-1 level of the two groups before and after treatment were statistically significant at time points and groups interaction(P<0.05).Comparison of simple effects LSD-t pairs showed,from a point of view,that the VAS score and TNF-α,IL-1 level of the two groups were significantly lower than those before treatment,and the JOA score AIMS2-SF score were significantly higher than before treatment(P<0.05).From the inter-group perspective,there was no significant difference in VAS score,JOA score,AIMS2-SF score and TNF-α,IL-1 level between the two groups before treatment(P>0.05);The VAS score and TNF-α,IL-1 level of the knee traction group after treatment were significantly lower than that of the manual traction group;JOA score and AIMS2-SF score were significantly higher than those of manual traction group(P<0.05).Grade rank sum test showed that there was no significant difference in overall curative efficacy between the two groups(P>0.05).However,the total effective cases of knee traction group were higher than that of manual traction group(P<0.05).Conclusion:Knee joint tractor is an effective method in clinical treatment of knee osteoarthritis.It can effectively relieve the pain degree of patients,reduce the level of TNF-α,IL-4 and promote the recovery of knee joint function and the quality of life of patients which is worthy of clinical promotion.