乌鲁木齐地区健康成人网织血小板参考区间的建立

Establish the reference interval of reticulated platelet for healthy adults in Urumqi

目的建立乌鲁木齐地区健康成人网织血小板的参考区间。方法以2019年9-12月在新疆医科大学附属肿瘤医院健康体检中心进行体检的1500例体检者为研究对象,取EDTA抗凝全血2mL,采用SYSMEX-XN9000血细胞分析仪检测网织血小板(RP)和网织血小板比例(IPF%),按性别、年龄分组采用SPSS19.0软件进行统计分析,得出RP和IPF%的参考区间。选取40名健康个体对建立的参考区间进行验证。结果RP和IPF%在乌鲁木齐健康成人中呈正偏态分布。RP和IPF%在男女间比较,差异无统计学意义(P=0.361,0.482)。RP和IPF%在18~35岁和36~60岁组间比较,差异无统计学意义(P=0.229,0.279)。RP乌鲁木齐健康成人参考区间为18~60岁(1.3×10^(9)~18.4×10^(9)/L),>60岁(0.8×10^(9)~14.9×10^(9)/L);IPF%乌鲁木齐健康成人参考区间为18~60岁(0.6%~7.3%),>60岁(0.5%~6.8%)。对所建立的RP和IPF%参考区间进行验证,验证结果100%通过。结论本研究为乌鲁木齐健康人群的RP和IPF%参考区间提供了数据支持。

Objective To establish the reference interval(RI)of reticulated platelet(RP)for healthy adults in Urumqi.Methods A total of 1500 patients underwent physical examination in Health examination center of the hospital fromSeptember 2019 to December were selected as the research objects.Sysmex-xn9000 hematology analyzer was used todetect the percentage of reticulated platelets(RP)and reticulated platelets(IPF%).According to gender and age,SPSS19.0 software was used for statistical analysis,and the reference intervals of RP and IPF%were obtained.40 healthy individuals were selected to verify the reference interval.Results RP and IPF%were distribution of positiveskewness in Urumqi healthy adults.There were no significant differences in RP and IPF%between men and women(P=0.361,0.482).There were no significant differences in RP and IPF%between 18~35 and 36~60 years old groups(P=0.229,0.279).The reference intervals of RP healthy adults in Urumqi were 1.3×10^(9)-18.4×10^(9)/L in 18-60 years old and 0.8×10^(9)-14.9×10^(9)/L in>60 years old;the reference intervals of IPF%healthy adults in Urumqi were0.6%-7.3%in 18-60 years old and 0.5%-6.8%in>60 years old.The established RP and IPF%reference intervalswere verified,and the results were 100%passed.Conclusion This study provides data support for RP and IPF%refer-ence intervals of healthy population in Urumqi.