不同主气时段出生与后天罹患不同病理组织学类型肺癌的关联性

Correlation between dominate qi of birth and the risk of different histopathological types of lung cancer

目的:探讨肺癌及其不同病理组织学类型罹患与出生时所属主气是否具有关联性。方法:基于2003年1月1日至2012年12月31日北京市33 025例肺癌患者发病资料,以同期北京中医药大学东直门医院非肿瘤病案资料为对照,将患者出生日期分别进行干支转化,推算出患者出生日期所属的主气时段。利用χ2检验比较肺癌患者人数在不同主气时段的分布情况,并采用无序多分类自变量的二分类Logistic回归,评估出生时间所属主气与罹患不同病理组织学类型肺癌的关系。结果:与终之气比较,出生于五之气时段的人群,罹患肺癌,以及肺鳞癌、其他非小细胞肺癌、小细胞肺癌的风险均增加(P<0.01,P<0.05)。结论:不同病理组织学类型肺癌的罹患与出生时的主气关联密切。

Objective: To explore whether the risk of suffering from various histopathological types of lung cancer is associated with dominate qi of birth. Methods: Based on the data of 33 025 lung cancer cases in Beijing from January 1, 2003 to December 31, 2012, and taking non-cancerous disease data of Dongzhimen Hospital, Beijing University of Chinese Medicine for the same period as the control, the date of birth of the patient was extracted and transformed it into heavenly stem and terrestrial branch, calculated the dominate qi period to which the date of birth belongs. Chi-square test was used to compare distribution of patients in different dominate qi periods. Logistic regression of disordered and multivariate independent variables was used to assess the relationship between the dominate qi of birth and lung cancer. Results: Compared with the 6 th qi, birth in the 5 th qi could increase the risk of lung cancer, including lung squamous cell carcinoma, other non-small cell lung cancer, and small cell lung cancer(P<0.01, P<0.05). Conclusion: The risk of suffering from various histopathological types of lung cancer is related to the dominate qi of birth.