摘要
半夏泻心汤记载于东汉张仲景所著《伤寒杂病论》,是中医经典方剂。近年来研究发现,其对胃癌具有良好的治疗作用,可减轻化疗所致的消化道反应,提高化疗患者的生活质量,促进胃癌术后患者的康复,还可治疗癌前病变,防止胃癌的发生;基础研究也表明,该方可调控胃癌细胞周期,诱导胃癌细胞凋亡,抑制胃癌细胞的增殖、侵袭、转移。文章就半夏泻心汤治疗胃癌的研究进展做一综述。
Banxia Xiexin Decoction, recorded in ZHANG Zhong-jing’s Shanghan Zabing Lun in the Eastern Han dynasty, is a classic prescription of traditional Chinese medicine. Recent studies have found that it has a good therapeutic effect on gastric cancer, it can alleviate the gastrointestinal reaction caused by chemotherapy, improve the quality of life of patients with chemotherapy, and promote the rehabilitation of patients with gastric cancer after operation, it can also treat precancerous lesions and prevent the occurrence of gastric cancer. Basic research also shows that this recipe can regulate the cell cycle of gastric cancer, induce apoptosis of gastric cancer cells, and inhibit the proliferation, invasion and metastasis of gastric cancer cells. The research progress of Banxia Xiexin Decoction in the treatment of gastric cancer was reviewed.
作者
刘宁宁
谈政
孙明瑜
李琦
LIU Ning-ning;TAN Zheng;SUN Ming-yu;LI Qiu(Department of Oncology,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Cancer Institute of Integrative Medicine,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Institute of Liver Diseases,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Institute of Integrated Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2020年第12期6254-6257,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
上海市进一步加快中医药事业发展三年行动计划项目[No.ZY(2018-2020)-CCCX-2003-02]
上海市自然科学基金项目(No.19ZR1458500)
上海市医学领军人才
上海市科委专项项目(No.15DZ1900104)
第四批全国中医优秀人才。
关键词
半夏泻心汤
胃癌
癌前病变
凋亡
Banxia Xiexin Decoction
Gastric cancer
Precancerous lesions
Apoptosis
