肺炎住院婴儿百日咳感染临床特点分析

Clinical Characteristics Analysis of Pertussis Infection of Hospitalized Infants With Pneumonia

目的对确诊百日咳婴儿临床特点进行研究,寻找百日咳临床早期诊断方法。分析常见病原体的感染情况。明确百日咳感染的危险因素。方法收集小于1周岁,因咳嗽而住院的患儿入组,并检测其百日咳杆菌及其他常见呼吸道感染病原体,填写临床调查表,总结目前我院婴幼儿百日咳杆菌及其他呼吸道病原体感染临床情况及特点。结果 MP感染及流感病毒AB感染,是<1周岁咳嗽住院患儿中感染率最高的两大病原体。临床表现及血常规特点是早期识别的关键。未进行免疫干预是感染百日咳的高危因素。结论应根据咳嗽患儿的年龄、疫苗接种情况、有无咳嗽接触史来评判百日咳的发生风险。尽早给予百日咳特异性治疗,监控传染源、防止严重并发症。

Objective To study clinical characteristics of infants diagnosed with pertussis,and find method for early clinical diagnosis of pertussis,analyzed infection of common pathogens,identify risk factors of pertussis infection.Methods Collect hospitalized children less than 1 year old due to cough in the study,and detect their pertussis bacilLi and other common respiratory tract infection pathogens,and fill in clinical questionnaires to summarize their clinical situation and characteristics of pertussis and other respiratory tract pathogens in our hospital.Results MP infection and influenza virus AB infection were two major pathogens with the highest infection rate in hospitalized children with cough less than 1 year old.Clinical manifestations and blood routine characteristics is key of early identification.No immune intervention is a high risk factor of pertussis.Conclusion It is necessary to evaluate risk of pertussis according to age,vaccination situation and cough contact history of of children with cough,and carry on specific treatment be as soon as possible,monitor infection source and prevent serious complications.