基于中医络病理论的亚健康失眠人群治未病干预效果评价

Intervention Effect Evaluation of Preventive Treatment on Sub-health Insomnia Based on TCM Collateral Disease Theory

目的通过络病理论指导,对门诊亚健康失眠患者行中医治未病手段干预,观察其甲皱微循环治疗前后的变化,评价防治手段效果。方法选取2017年1月至2018年9月门诊亚健康失眠(气郁质)患者120例,随机分为治未病组、西药组各60例,治未病组予中药内服及中医适宜技术干预治疗(耳穴敷贴),西药组予舒乐安定,疗程为2周,共2个疗程。对比患者治疗前后管襻数、管长、管径、流速、流态等甲皱微循环指标变化情况。结果亚健康失眠(气郁质)患者治疗前存在甲皱微循环异常,治未病组、西药组治疗后各指标较治疗前均有改善,并具有明显差异(P<0.05),治未病组优于西药组(P<0.05)。治未病组临床疗效总有效率为93.33%,西药组临床总有效率为76.67%,两者具有明显差异(P<0.05)。结论中医络病理论指导下的中医治未病干预能有效改善亚健康失眠(气郁质)患者的甲皱微循环情况,并取得良好的临床疗效。

Objective To carry out intervention on subhealth insomnia patients with TCM preventive measures,observe changes of nail fold microcirculation before and after treatment,and evaluate prevention and treatment effect based on collateral disease theory.Methods We chose 120 cases of outpatients with sub-health insomnia (Qi stagnation syndrome) from January 2017 to September 2018,divided them into preventive treatment group and western medicine group randomly,with 60 cases in each group.Preventive treatment group was treated with oral Chinese medicine and appropriate Chinese medicine technology intervention (auricular point application),while western medicine group with zolepam for 2 weeks,with a total of 2 courses.Compared changes of nail fold microcirculation indexes before and after treatment,such as number of tube loops,tube length,diameter,flow rate and flow pattern.Results There were abnormal nail fold microcirculation in patients with sub-health insomnia (Qi stagnation constitution) before treatment.Indexes of preventive treatment group and western medicine group were significantly better than before treatment (P<0.05),and these of preventive treatment group were better than those of western medicine group (P<0.05).Total effective rate was 93.33% in preventive treatment group and 76.67% in western medicine group,with significant difference (P<0.05).Conclusion TCM preventive intervention under guidance of collateral disease theory can improve nail fold microcirculation of patients with sub-health insomnia (qi stagnation) effectively,and achieve good clinical effect.