2型糖尿病患者颈动脉粥样硬化的危险因素分析

Analysis of Risk Factors of Carotid Atherosclerosis in Type 2 Diabetes

目的分析2型糖尿病患者发生颈动脉粥样硬化的危险因素。方法方便选择于2017年3月—2018年12月在该院内分泌科住院的124例2型糖尿病患者,根据颈动脉彩超有无颈动脉粥样硬化分为病变组(65例)及对照组(59例),比较两组基本资料和生化指标,应用Logistic回归分析颈动脉粥样硬化相关影响因素。结果颈动脉粥样硬化病变组,年龄(64.39±8.26)岁、糖尿病病程(12.47±5.13)年、高血压史45例(69.23%)、餐后2 h血糖(16.35±3.51)mmol/L、糖化血红蛋白(9.43±1.24)%、低密度脂蛋白(3.38±0.46)mmol/L与对照组比较,差异有统计学意义(t=5.526、8.099,χ^(2)=6.995,t=3.878、5.024、2.805,P<0.05)。Logistic回归分析显示,年龄、糖尿病病程、高血压史是糖尿病患者发生颈动脉粥样硬化的危险因素。结论年龄、糖尿病病程、高血压史是2型糖尿病患者颈动脉粥样硬化的影响因素,注重早期干预控制,对糖尿病大血管病变的防治有重要意义。

Objective To analyze the risk factors of carotid atherosclerosis in patients with type 2 diabetes.Methods A total of 124 patients with type 2 diabetes who were conveniently selected in the Department of Endocrinology in the hospital from March 2017 to December 2018 were collected.According to the presence or absence of carotid artery atherosclerosis,they were divided into diseased group(65 cases)and control group(59 cases),compared the basic data and biochemical indicators of the two groups,and used Logistic regression to analyze the related factors of carotid atherosclerosis.Results Carotid atherosclerosis group,age(64.39±8.26)years old,course of diabetes(12.47±5.13)years,history of hypertension,45 cases(69.23%),2 h postprandial blood glucose(16.35±3.51)mmol/L,glycation Hemoglobin(9.43±1.24)%and low-density lipoprotein(3.38±0.46)mmol/L were statistically different from the control group,the difference was statistically significant(t=5.526,8.099,χ^(2)=6.995,t=3.878、5.024,2.805,P<0.05).Logistic regression analysis showed that age,course of diabetes and history of hypertension were risk factors for carotid atherosclerosis in diabetic patients.Conclusion Age,course of diabetes,and history of hypertension are the influencing factors of carotid atherosclerosis in patients with type 2 diabetes.Paying attention to early intervention and control is of great significance to the prevention and treatment of diabetic macrovascular disease.