慢性阻塞性肺疾病急性加重期的临床治疗分析

Analysis of Clinical Treatment in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的探讨慢性阻塞性肺疾病(COPD)的临床治疗方法及治疗效果。方法方便选取该院2017年10月—2019年10月期间收治的106例COPD急性加重期患者作为研究对象,应用单盲随机法,分为观察组(常规+雾化吸入治疗)和对照组(常规治疗),各53例,对比两组患者的治疗效果。结果与对照组相比,观察组患者的第1秒用力呼气容积(FEV1)水平[(2.47±0.52)L>(2.12±0.59)L]、第一秒用力呼气量占所有呼气量的比例(FEV1/FVC)水平[(68.32±4.06)%>(56.35±3.97)%]以及治疗有效率94.34%>77.36%相对更高,差异有统计学意义(t=3.240,15.346,χ^(2)=6.290,P<0.05),症状消失时间[(6.02±1.17)d<(9.23±1.54)d]、住院时间[(9.06±0.94)d<(12.15±1.06)d]相对更短,差异有统计学意义(t=12.083、15.878,P<0.05)。结论常规+雾化吸入治疗在COPD患者中的应用,在改善临床症状和促进呼吸功能恢复方面具有显著的作用效果。

Objective To explore the clinical treatment methods and therapeutic effects of chronic obstructive pulmonary disease(COPD).Methods A total of 106 patients with acute exacerbation of COPD who were admitted to the hospital from October 2017 to October 2019 were selected as the research objects.They were divided into observation group(conventional+nebulized inhalation therapy)and control group(conventional treatment),53 cases in eachgroup,and compared the treatment effects of the two groups of patients.Results Compared with the control group,the observation group's forced expiratory volume in the first second(FEV1)level[(2.47±0.52)L>(2.12±0.59)L],the forced expiratory volume in the first second proportion of total expiratory volume(FEV1/FVC)level[(68.32±4.06)%>(56.35±3.97)%]and the treatment effective rate 94.34%>77.36%was relatively higher,the difference was statistically significant(t=3.240,15.346,χ^(2)=6.290,P<0.05),symptom disappearance time[(6.02±1.17)d<(9.23±1.54)d],hospitalization time[(9.06±0.94)d<(12.15±1.06)d],relatively shorter,the difference was statistically significant(t=12.083,15.878,P<0.05).Conclusion The application of conventional+nebulized inhalation therapy in COPD patients has a significant effect in improving clinical symptoms and promoting the recovery of respiratory function.