绝经后妇女髋部几何力学参数与生活习惯的相关性

Correlation between hip geometric mechanics and lifestyle habits in postmenopausal women

背景:在骨质疏松症研究中已有众多文献对于骨密度进行报道,但仍未能充分说明骨强度以及骨折的问题,此文基于髋部力学来研究骨强度,希望对现有的研究有所补充。目的:了解绝经后妇女的生活习惯对髋部几何力学的影响。方法:选取648例绝经后妇女,均使用双能X射线数字化骨密度仪扫描腰椎(L1-L4)及左髋关节(全髋、股骨近端),并得出相应的骨密度值及髋部几何力学5个参数:骨横截面积、横截面转动惯量、截面弯曲模量、皮质厚度和屈曲应力比。采用线性分析法分析生活习惯与骨密度值及髋部几何力学的相关性。结果与结论:①影响骨密度的因素分析:年龄、每天喝2杯以上咖啡及怀孕次数与骨密度呈负相关(P<0.05);体质量、体质量指数及中强度的运动与骨密度呈正相关(P<0.05);②影响髋部几何力学的因素分析:年龄、每天喝咖啡与骨横截面积、横截面转动惯量、截面弯曲模量、皮质厚度呈负相关(P<0.05),年龄、每天喝咖啡及每天少于1杯牛奶与屈曲应力比呈正相关(P<0.05);体质量、身高、日照时间大于3 h及中强度运动与骨横截面积、横截面转动惯量、截面弯曲模量、皮质厚度呈正相关(P<0.05);体质量指数与屈曲应力比呈负相关(P<0.05);③提示每天喝咖啡不利于骨质健康,适当的运动有助于骨质健康,日照时间大于3 h才可以增加骨强度。

BACKGROUND:There are many reports about bone mineral density in the study of osteoporosis,but it still cannot fully explain the problems of bone strength and fracture.This paper studies bone strength through hip mechanics,hoping to supplement the existing research.OBJECTIVE:To understand the impact of postmenopausal women’s lifestyle habits on hip geometry and mechanics.METHODS:Totally 648 postmenopausal women were selected.The subjects used dual-energy X-ray digital bone density to scan the lumbar spine(L1-L4)and left hip joint(total hip,proximal femur),and obtained the corresponding bone mineral density value and five parameters of hip geometric mechanics:bone cross-sectional area,cross-sectional rotational inertia,cross-sectional flexural modulus,cortical thickness and buckling stress ratio.Linear analysis was conducted to analyze the correlation of lifestyle habits with bone mineral density and hip geometry mechanics.RESULTS AND CONCLUSION:(1)Analysis of factors affecting bone density:Age,drinking more than two cups of coffee per day,and the number of pregnancies were negatively correlated with bone density(P<0.05);body weight,body mass index,and moderate-intensity exercise were positively correlated with bone density(P<0.05).(2)Factor analysis of affecting hip geometric mechanics:age and daily coffee consumption were negatively correlated with cross-sectional area,cross-sectional rotational inertia,cross-sectional flexural modulus,and cortical thickness(P<0.05).Age,daily coffee consumption and less than one cup of milk per day were positively correlated with buckling stress ratio(P<0.05).Body weight,height,and sunshine duration greater than 3 hours and moderateintensity exercise were positively correlated with cross-sectional area,cross-sectional rotational inertia,cross-sectional flexural modulus,cortical thickness(P<0.05).Body mass index was negatively correlated with buckling stress ratio(P<0.05).(3)It is indicated that drinking coffee every day is not conducive to bone health;proper exercise can help bone health;sunshine time greater than 3 hours can increase bone strength.