基于VOSviewer与CiteSpace对内质网应激研究的知识图谱分析

Analysis of knowledge graph of endoplasmic reticulum stress research based on VOSviewer and CiteSpace

目的分析近10年内质网应激的研究现状、经典文献、热点和前沿。方法检索自2010年1月—2020年9月收录于Web of Science(WOS)数据库中的内质网应激相关文献,借助VOSviewer和CiteSpaceⅤ软件对该领域的发文量、文献共被引、关键词、关键词突发检测和时区图进行可视化分析。结果纳入22021篇SCI文献,发文量呈逐年上升趋势,文献被引量最多的是David等文章,研究热点为细胞自噬与凋亡、氧化应激、未折叠蛋白等。结论本文揭示了近10年来该领域的研究力量、发展脉络、研究热点和前沿,为今后学者的研究提供参考。

Objective To analyze the research status,classic literature,hot spots and frontiers of endoplasmic reticulum stress in the past 10 years.Methods The literature on endoplasmic reticulum stress included in the Web of Science database were retrieved from January 2010 to September 2020,while VOSviewer and CiteSpaceⅤsoftware were used to study the number of publications,literature citations,keywords,keyword burst detection and time zone diagram for visual analysis.Results A total of 22021 SCI articles were included.The amount of publications was increasing year by year.The articles of David et al.were cited the most.The research hotspots were focused on autophagy and apoptosis,oxidative stress,unfolded protein,etc.Conclusion This article reveals the research strength,development context,research hotspots and frontiers of this field in the past 10 years,and provides references for future scholars’research.